PURPOSE To study the effects of long-term treatment with potassium magnesium citrate and vitamin B-6 prophylaxis (Urikind-KM6; 1,100-mg potassium citrate, 375-mg magnesium citrate, and 20-mg pyridoxine hydrochloride/5 mL) every 8 hours over 3 years. MATERIALS AND METHODS A total of 247 patients with recurrent idiopathic hypocitraturia with or without hyperuricosuria and randomized controls we...

OBJECTIVE To evaluate the prevalence of metabolic disorders associated with nephrolithiasis in a female population. METHODS A retrospective study on 1,737 patients with evidence of recent formation of renal stones, being 54% females. The laboratory investigation consisted of at least two samples of blood and 24-hour urine to assess calcium, uric acid, citrate and creatinine levels, qualitativ...

OBJECTIVE To assess the prevalence of the main metabolic alterations found in patients with recent diagnosis of urolithiasis in the West region of Parana state, Brazil. MATERIALS AND METHODS We made a retrospective study on 425 patients with evidence of recent formation of renal stones. Laboratory assessment consisted in 3 samples of 24-hour urine with dosing of calcium, uric acid, citrate, o...

in spite of vast improvements in urinary stone treatment (eswl, pnl, ureteroscopy, etc.), metabolic workup concerning the existence of stone forming risk factors are of great importance and can lead to control and even prevention of urinary stone formation in these patients. in this analytical case-control study performed on 266 persons [110 normal persons (56 males and 54 females), 76 patients...

Citrate is a weak acid that is formed in the tricarboxylic acid cycle or that may be introduced with diet. In the present paper all the mechanisms involved in intestinal absorption, renal handling and modulation of citrate will be reviewed. The evaluation of plasma citric acid is scarcely used in the diagnosis of human diseases. On the contrary urinary citrate excretion is a common tool in the ...

Objective: To determine the frequency of various metabolic abnormalities in children with urinary lithiasis. Methods: This cross-sectional study was conducted at Armed Forces Institute Urology, Rawalpindi, from 30 January 2017 to 1 February 2020. A total 1355 who were aged 4 14 years and had renal stones included, while those tract infections, posterior urethral valve, pelvi-ureteric junction o...

Background The prevalence of urolithiasis in both infants and children is increasing. The metabolic features contributing to urolithiasis formation in children may vary from those in adult patients. The purpose of this study is to determine the prevalence of urinary metabolic abnormalities and related factors in infants and children with urolit...