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Molar-incisor hypomineralization (MIH) is a condition that is defined based on its peculiar clinical presentation. Reports on the etiology of the condition and possible risk factors are inconclusive and the original suggestion that MIH is an idiopathic condition is often cited. Our group was the first to suggest MIH has a genetic component that involves genetic variation in genes expressed duri...

Molar incisor hypomineralization (MIH) is a common developmental condition resulting in enamel defects in first permanent molars and permanent incisors. It presents at eruption of these teeth. One to four molars, and often also the incisors, could be affected. Since first recognized, the condition has been puzzling and interpreted as a distinct phenomenon unlike other enamel disturbances. Early...

AIMS To determine the prevalence of molar incisor hypomineralization (MIH) in Indian children and to analyze the possible etiological factors. MATERIALS AND METHODS First permanent molars and all permanent incisors were examined in 1,369 children aged 8 to 12 years. Examinations were performed by two calibrated observers. The subjects were evaluated using judgment criteria proposed by Weerhei...

Background: Many clinicians tell me they are seeing more enamel hypoplasia in permanent first molars these days. Some have speculated as to why this may be occurring, with many differing hypotheses emerging. Recently, others have speculated that the recent increase in the use of certain antibiotics in early childhood could have a mineralization effect on permanent first molars and incisors, whi...

Molar incisor hypomineralization (MIH) is a congenital disease which is increasing in prevalence. It affects permanent first molars and, often to a lesser degree, permanent incisors with variable severity. The etiology is unknown, but various risk factors have been put forward. Differential diagnosis is mandatory not to confound MIH with other diseases such as amelogenesis imperfecta or fluoros...

BACKGROUND/AIM Hypomineralization of molars and incisors (molarincisor hypomineralization--MIH) is defined as enamel hypomineralization of systemic origin of one or more of the four first permanent molars, which may be associated with changes in the maxillary, and less frequently in the permanent mandibular in cisors. The aim of this study was to investigate the mineral content in hypomineraliz...

The aim of this study was to investigate the segregation patterns molar incisor hypomineralization (MIH) in families, given evidence that its etiology is influenced by genetics. Clinically, MIH may be detected parents and/or siblings MIH-affected children. Our included children with at least one first permanent affected (proband) and their first-degree relatives (parents siblings). participants...

Purpose: Molar Incisor Hypomineralization (MIH) is a congenital defect of unknown etiology that has been recently identified and is currently considered an increasing concern to dental clinicians. The defect involves enamel mineralization of one to four permanent first molars usually associated with similarly affected permanent incisors. The purpose of this retrospective study was to investigat...