amyloidosis cutis dyschromica (acd) is a rare form of macular amyloidosis characterized by hypo and hyperpigmented macules. here we described a 20 year old girl with diffuse hypo and hyperpigmentation since she was four years old. five other members of her family are also involved. biopsy of hyperpigmented lesions revealed increase of melanin in the basal layer, pigment incontinence and amorpho...

A 4 year old boy is reported with tyrosinase positive hypopigmentation, mental retardation, ataxia, and myopia. Radiological investigation showed occipital cerebral atrophy, coxa valga, and generalised osteoporosis. The skin histology and electron microscopy are reported and discussed. The clinical features are similar to those of the oculocerebral hypopigmentation syndrome described by Preus e...

Sir, Imatinib mesylate is a tyrosine kinase inhibitor that targets BCR-ABL protein in chronic myelogenous leukemia (CML).1 We present three cases of CML, treated with Imatinib who developed clinical findings of hypopigmentation. All the three patients noticed pigmentation changes after the initiation of therapy with Imatinib mesylate, which was persistent during therapy. The presence of hypopig...

43 How to cite this article: Acharya R, Gyawalee M. Uncommon presentation of Pityriasis versicolor; hyper and hypopigmentation in a same patient with variable treatment response. Our Dermatol Online. 2017;8(1):43-45. Submission: 20.02.2016; Acceptance: 06.06.2016 DOI:10.7241/ourd.20171.11 Uncommon presentation of Pityriasis versicolor; hyper and hypopigmentation in a same patient with variable ...

Background:-Hypopigmentary disorders constitute a large and heterogenous group of diseases that are clinically characterised by hypopigmented macules .Dermoscopy is non invasive imaging technique allows for appreciation subtle, distinctive features visible to the naked eye aid in differential diagnosis hypopigmentary disorders. Aims &Objective:- To investigate utility dermoscopy In common d...

Background Increasing evidence suggests that degeneration of Locus Coeruleus (LC) neurons is a common feature various neurodegenerative diseases. Including patients neuropathologically diagnosed with frontotemporal lobar (FTLD). Based on the histopathological patterns FTLD has been categorized into three distinct subtypes; tau immunoreactivity inclusion (FTLD-tau), TDP-43 (transactive response ...