نتایج جستجو برای: iadc
تعداد نتایج: 11 فیلتر نتایج به سال:
Journal:
:American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
2005
Peter Holmans
Marian Hamshere
Paul Hollingworth
Frances Rice
Nigel Tunstall
Sue Jones
Pamela Moore
Fabienne Wavrant DeVrieze
Amanda Myers
Richard Crook
Danielle Compton
Helen Marshall
David Meyer
Shantia Shears
Jeremy Booth
Dzanan Ramic
Nigel Williams
Nadine Norton
Richard Abraham
Pat Kehoe
Hywel Williams
Varuni Rudrasingham
Mick O'Donovan
Lesley Jones
John Hardy
Alison Goate
Simon Lovestone
Michael Owen
Julie Williams
We performed an affected sib-pair (ASP) linkage analysis to test for the effects of age at onset (AAO), rate of decline (ROD), and Apolipoprotein E (APOE) genotype on linkage to late-onset Alzheimer's disease (AD) in a sample comprising 428 sib-pairs. We observed linkage of mean AAO to chromosome 21 in the whole sample (max LOD = 2.57). This came entirely from the NIMH sample (max LOD = 3.62), ...
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