BACKGROUND In this study, we evaluated the prevalence of primary resistance of Brazilian H. pylori isolates to metronidazole, clarithromycin, amoxicillin, tetracycline, and furazolidone. In addition, the vacA, iceA, cagA and cagE genotypes of strains isolated from Brazilian patients were determined and associated with clinical data in an effort to correlate these four virulence markers and anti...

Infection with Helicobacter pylori strains harboring determinants of pathogenicity may lead to a strong inflammatory response in gastric mucosa. In this work, we examined the frequency of the cagA, vacA and iceA genotypes in H. pylori strains isolated from Brazilian patients and correlated these with the clinical manifestations. H. pylori was isolated from 165 patients [30 with non-ulcer dyspep...

helicobacter pylori has been strongly associated with peptic ulcer diseases, chronic gastritis, ulcers, and reported as a risk factor for gastric cancer, too. the vaculating cytotoxin (vaca), the cytotoxin associated genes (caga), the induced by contact with epithelium factor antigen (icea gene), blood adhesion binding antigen (baba2), and outer membrane protein oipa have been described as diff...

This study identified pathogenicity genes in 40 Helicobacter pylori clinical isolates. The cagA, vacA, and iceA genes were detected in 65%, 97.5%, and 97.5% of the isolates, respectively. The cagA, iceA1, and vacAs1a/m1 genes were related to erosive gastritis, whereas the vacAs2/m2 and iceA2 genes were associated with enanthematous gastritis.

From the ‡Laboratoire de Bioénergétique et Ingénierie des Protéines CNRS UPR 9036, Institut de Biologie Structurale et Microbiologie, 31 Chemin Joseph Aiguier, F-13402 Marseille Cedex 20, ¶Section de Bioénergétique, Département de Biologie Cellulaire et Moléculaire, CEA Saclay, F-91191 Gif sur Yvette Cedex, and iCEA/Cadarache, DSV-DEVMLaboratoire de Bioénergétique Cellulaire, F-13108 Saint Paul...

Infection with Helicobacter pylori is a major cause of chronic gastritis and peptic ulcer disease in children and its consequences in adulthood can lead to serious complications, including in particular the development of gastric cancer. Our aim was to analyze the relationship between the occurrence of selected genes such as cagA, vacA, iceA, and babA2 determining pathogenicity of H. pylori str...

The genotypes of Helicobacter pylori flaA, cagA, vacA, and iceA were determined for DNA isolated from patients with chronic gastritis or peptic ulcer in eastern Taiwan. The vacA gene encoding the s1a subtype was found to predominate in peptic ulcer patients, and the iceA1 genotype was associated with chronic gastritis. cagA and flaA genes were not found to be associated with these types of dise...

Purpose (1) A concern often expressed in relation to cryptocurrencies is the environmental impact associated with increasing energy consumption and mining pollution. Controversy remains regarding how attention public concerns adversely affect cryptocurrency prices. Therefore, paper aims introduce index of (ICEA), which capture relative extent media discussions surrounding cryptocurrencies. (2) ...