Two cases of neonatal hepatitis are described, one related to cytomegalovirus infection and the other idiopathic. In both infants a transient abnormality of the alpha 1-antitrypsin phenotype, inconsistent with the parent's phenotypes, reverted to normal during the convalescent phase of the illness.

background: idiopathic thrombocytopenic purpura (itp) is a disease that commonly affects women of reproductive age and is associated with maternal and fetal complications. objective: the aim of the present study was to report the perinatal outcome in pregnant women with itp. materials and methods: twenty one pregnant women with itp admitted in a teaching hospital in tehran, from october 2008 to...

One hundred and three infants with prolonged cholestasis beginning before 3 months were classified as having alpha-1-antitrypsin deficiency (17 patients), scanty interlobular bile ducts (16 patients), or "neonatal hepatitis" (70 patients). Twenty-two gradually developed chronic liver disease and the remaining 81 recovered within a few months. Prognosis was found to be poor for infants with alph...

Biliary lipid compositions in infants with cholestasis were analysed. Bile acid and phospholipid values were appreciably lower in infants with idiopathic neonatal hepatitis syndrome or corrected biliary atresia than in control infants. Cholesterol values were not, however, notably lower in infants with cholestasis. When biliary lipid components were determined in terms of molar percent, bile ac...

During a period of three years from 1996 to 1998, 124 infants (64 male and 60 female) with an age range of 1-6 months (mean age 1.5 months) with cholestasis were studied. Idiopathic neonatal hepatitis was the most common cause of cholestasis, accounting for 48 cases with a rate of 3'8.70% in a total of 124 patients, followed by galactosemia in 29 patients (23.38%) and extrahepatic biliary ...

AIM To retrospectively analyze different methods in differentiating biliary atresia from idiopathic neonatal hepatitis. METHODS Sixty-nine infants with cholestatic jaundice and final diagnosis of idiopathic neonatal hepatitis (INH) and biliary atresia (BA) were studied retroprospectively from January 2004 to December 2006. A thorough history and physical examination were undertaken. All cases...

Received August 3, 2007 Abstract Background and Aim: The significance of serum gamma glutamyltransferase activity and its dynamics have not been well investigated in Asian patients with idiopathic neonatal hepatitis. This study aimed to explore the significance in Mainland China. Methods: A retrospective analysis was performed in 38 cases with a diagnosis of idiopathic neonatal hepatitis. Their...

introduction:  inadequate intake of breast milk in the first days of life leads to weight loss in neonates. jaundice is also more prominent in these infants. in this cross-sectional study, we tried to evaluate the extent of weight loss in term breastfed infants who were hospitalized for idiopathic hyperbilirubinemia. methods: this prospective study involved 1072 infants >48 hours old, who were ...

Background: Aflatoxin B 1 induced hepatitis was reported to be associated with characteristic features of centrizonal scarring, hepatic venous occlusion, ductular proliferation and cholestasis, focal syncytial giant cell giant cell transformation of hepatocytes, and pericelluar fibrosis which is congruent to biopsy findings in extra hepatic biliary atresia (EHBA). Aim of Work: Is to study aflat...