Small fragments circulating in the blood were formally identified by the end of the nineteenth century, and it was suggested that they assisted coagulation via interactions with vessel endothelia. Wright, at the beginning of the twentieth century, identified their bone-marrow origin. For long, platelets have been considered sticky assistants of hemostasis and pollutants of blood or tissue sampl...

A. Does the project require specialized equipment or facilities? A2. If yes, has access been arranged? List the P.I. providing these resources as a collaborator above. B. Is additional funding required for this project? B2. If yes, has this been obtained? Source of funding and amount ___________________________________ C. Does the project require work in a laboratory? C2. If yes, do all persons...

Solution: Yes; for instance consider the language L = {5}, i.e., the language containing a single element and the corresponding decision problem: D1: Does x ∈ L?. I can reduce an arbitrary decision problem D2 ∈ P to D1 using the reduction f , which is defined as follows: Given x as input to D2, f first checks in polynomial time, whether x ∈ D1. If x is a “yes” instance of D2, f(x) = 5; otherwis...

Fever ≥38.5°C No/U Yes 0 Enlarged lymph nodes No/U Yes 0 Eosinophils No/U 0.7–1.499 × 109l–1 ≥ 1.5× 109l–1 1 Atypical lymphocytes No/U Yes 1 Skin involvement 2 Skin rash extent (% body surface area) No/U > 50% Skin rash suggesting DRESS No/U Yes Biopsy suggesting DRESS No Yes/U Organ involvementa 2 Liver No/U Yes Yes Kidney No/U Yes No/U Lung No/U Yes Yes Muscle/heart No/U Yes No/U Pancreas No/...