DNA polymorphism within diacylglycerol transferase 2 (DGAT2) / monoacyl glycerol transferases 2 (MOGAT2), leptin and butyrophilin genes were analysed using PCR-SSCP in Murrah buffalo. The single strand conformation polymorphism (SSCP) analysis of amplified gene fragment in exon 5 of MOGAT2, exon 3 of leptin and intron 1 of butyrophilin gene revealed different patterns. A, B and C showed the fol...

background:it has been hypothesized that genetic factors other than histocompatibility disparity may play a role in predisposition to developing chronic myelogenous leukemia (cml). in this regard, th1 and th2 cytokines and their gene polymorphism seems to be important. overall expression and secretion of cytokines is dependent, at least in part, on genetic polymorphism (nucleotide variations) w...

The angiotensin-converting enzyme (ACE) gene consists of 26 exons, it is located on chromosome 17 and its polymorphism a major contributing factor to hypertension. aim compare the efficacy Chlorthalidone Azilsartan in newly diagnosed hypertension patients association with ACE polymorphism. study was conducted department pharmacology, Rama medical college, Kanpur. After doing genetic test basic ...

dna polymorphism within diacylglycerol transferase 2 (dgat2) / monoacyl glycerol transferases 2 (mogat2), leptin and butyrophilin genes were analysed using pcr-sscp in murrah buffalo. the single strand conformation polymorphism (sscp) analysis of amplified gene fragment in exon 5 of mogat2, exon 3 of leptin and intron 1 of butyrophilin gene revealed different patterns. a, b and c showed the fol...

Background Varicocele is an abnormal dilation and tortuosity of veins of pampiniform plexus that drains the testis and causes an important change in semen.This abnormality is often one of the most common risk factors for male infertility. The aim of this study was to investigate the relationship between nitric oxide synthase 3 (NOS3) 4a4b (rs61722009) gene polymorphism, as a common genetic fact...

Background: Angiotensin converting enzyme (ACE) is the key enzyme, regulates blood pressure which encoded by 21kb gene that consists of 26 exons and located on chromosome 17, contains a polymorphism in form either Insertion (I) or Deletion (D). The aim was to study effect antihypertensive drugs patients essential hypertension associated with ACE polymorphism. Methods: Hypertensive were recruite...

background tuberculosis (tb) is one of the earliest human diseases which still is considered a public health problem. both genetic and environmental factors may contribute the susceptibility to tuberculosis. objectives akt is a serine/threonine kinase that has an important role in several cellular processes such as cell cycle control, cell survival, and cellular immigration. the akt signaling p...

background almost one-third of the world's population is infected with mycobacterium tuberculosis, but only 10% of them develop tuberculosis. tnf-α/il-10 balance has key roles in controlling latent/activation stages of tuberculosis. objectives the objective of this study was to determine an association between polymorphic variants of the tnf-α and il-10 genes and tuberculosis. patients and meth...