cus aureus by heat shock. The effect has then been more thoroughly investigated by landolo and Ordal (5, 6). Since heat shock causes an increased sensitivity of fungal cells to high temperature and blue light (2-4), it seemed justified also to test the response of heat-shocked fungal cells to high concentrations of sodium chloride. Most experiments were performed with the ascomycete Ophiostoma ...

A new series of D-π-A type imidazole derivatives have been synthesized and characterized. Two corresponding imidazolium salts (iodine and hexafluorophosphate) were prepared from the imidazole compound. Their electron-withdrawing ability can be largely tunable by salt formation reaction or ion exchange. UV-vis absorption and single-photon fluorescence spectra have been systematically investigate...

Low-temperature studies of the simple variously substituted imidazole types 4-phenyl-1H-imidazole, C9H8N2, 1-benzyl-1Himidazole, C10H10N2, and 1-mesityl-1H-imidazole, C12H14N2, extend comparisons between parent imidazole species and their derivatives, the pronounced double-bond localization opposite the substituted N atom common to simple neutral species being redistributed aromatically on prot...

Five optically active imidazole derivatives have been synthesized via a facile 4-step reaction sequence starting from commercially available and inexpensive N-Cbz amino acids. While microwave assisted condensation was unsuccessful, the condensation of the corresponding alpha-bromoketones with formamidine acetate in liquid ammonia was revealed to be a useful method for the synthesis of such imid...

The synthesis of imidazole styrylbenzamide, tert-butyl styrylimidazole, and tert-butyl styrylsulfonate derivatives is described. Evaluation of binding affinity and inhibitory activity against CYP24A1 identified the imidazole styrylbenzamides as potent inhibitors of CYP24A1, having selectivity with respect to CYP27B1 comparable with or greater than that of the standard ketoconazole. Further eval...

Intermediates formed during the microbial degradation of imidazole, namely 4(5)-imidazolone, formiminoglycine, and possibly glycine, are similar to those formed during metabolism of imidazole derivatives.

Photo-oxidation reactions of imidazole derivatives accelerated by quinoid oxidation-state structures, which can be controlled different linking types arylamine groups.

Background and objective: Six families of thiazole, thiazolidine, imidazole, tetrahydropyrimidine, oxazolidine and thiazepine are new and important heterocyclic antibacterial compounds. Aim of this study is evalution the antibacterial effect of thirty new thiazole, thiazolidine, imidazole, tetrahydropyrimidine, oxazolidine and thiazepine derivatives against Bacillus subtilis and salmonella ente...

Introduction: Imidazole is an entity which is being synthesized in many of its derivative form from past few years; the entity is major source of interest for many of medicinal chemist to explore its various pharmacological potentials. In present article we review the chemistry of imidazole and its pharmacological actions as antihelmintics, anticancer, antifungal and anti-inflammatory agent by ...