OBJECTIVES To study acute exposure to imidazoline derivatives in 72 children younger than 15 years of age, followed-up from January 1994 to December 1999. METHODS This is a retrospective study of 72 patients with age between 2 months and 13 years (median 2 years; 25-75% = 1 to 3 years old) exposed to naphazoline (N = 48), fenoxazoline (N = 18), oxymetazoline (N = 5) and tetrahydrozoline (N = ...

Dowex-50W-hyodrgen ion exchange resin was used as a reusable catalyst for the synthesis of oxazoline, imidazoline and thiazoline derivatives through condensation reaction between arylnitriles and 2-aminoalcohol, ethylenediamine or 2-aminoethanthiol. This process provides several advantages such as excellent yields of the products, simple operation, convenient separation and inexpensive and recy...

TVP1022, the S-enantiomer of rasagiline (Azilect®) (N-propargyl-1R-aminoindan), exerts cyto/cardio-protective effects in a variety of experimental cardiac and neuronal models. Previous studies have demonstrated that the protective activity of TVP1022 and other propargyl derivatives involve the activation of p42/44 mitogen-activated protein kinase (MAPK) signaling pathway. In the current study, ...

The syntheses and structures of copper(i) chalcogenone complexes are described. The homoleptic mononuclear copper(i) complexes [(IPr[double bond, length as m-dash]E)2Cu]ClO4, IPr[double bond, length as m-dash]E, 1,3-bis(2,6-diisopropylphenyl)imidazoline-2-thione (1) and 1,3-bis(2,6-diisopropylphenyl)imidazoline-2-selone (2); [(IMes[double bond, length as m-dash]E)2Cu]ClO4, IMes[double bond, len...

The mixture of Synthetic Petroleum Acids (SPA) and oxyacids (OSPA) have been synthesized on the basis of naphthenic-paraffinic hydrocarbons separated from 217-349°C fractions of Azerbaijan oils in the presence of the salts of Natural Petroleum Acids (NPA). The acid number of the obtained (SPA+OSPA) was 165 mgKOH/g, the yield was 40%. Imidazoline derivatives have been synthesized based on the mi...

Silathiazolidine and metalladithioacetals (M = Si, Ge) have been prepared by the interaction of dialkyldichloro- or bis(diethylamino)dialkylsilanes and -germanes with 3-[N-(2- thioethyl)]amino-propanamide (WR-2529) and [1-thioethyl-2-(1-naphtylmethyl)]-2- imidazoline. The study of these compounds in the field of chemical radioprotection has shown a notable decrease in the toxicity and a rather ...

Under controlled conditions the effects of various "sympatholytic" agents on the cardiovascular responses to epinephrine and norepinephrine were compared in man. The dosages of the sympatholytic drugs administered approximated those usually employed clinically. Such basic data are given for the following agents: Dibenamine, the imidazoline derivatives [Priscoline and Regitine (C-7337)], the dih...

Under controlled conditions the effects of various "sympatholytic" agents on the cardiovascular responses to epinephrine and norepinephrine were compared in man. The dosages of the sympatholytic drugs administered approximated those usually employed clinically. Such basic data are given for the following agents: Dibenamine, the imidazoline derivatives [Priscoline and Regitine (C-7337)], the dih...