Immune thrombocytopenic purpura (ITP) patients are at high risk for bleeding complications regarding surgeries involving cardiopulmonary bypass. We report an ITP patient with chronic thromboembolic pulmonary hypertension who underwent uncomplicated pulmonary endarterectomy with receiving postoperative intravenous immunoglobulin (IVIG) therapy. The positive outcome of this case may suggest that ...

About 25-30% of patients with immune thrombocytopenic purpura (ITP) are refractory to corticosteroids, splenectomy and other treatments. It has been suggested that interferon-alpha 2b (IFN-alpha 2b) may be useful in the treatment of chronic refractory ITP patients. We treated 9 chronic refractory ITP patients with IFN-alpha 2b: the results were poor.

Spontaneous intracranial haemorrhage (ICH) is a rare complication of chronic immune thrombocytopenic purpura (ITP) in children. We report four patients with cITP who developed ICH. The latency between onset of ITP and ICH varied from 1-8 years. All our patients were profoundly thrombocytopenic (platelet count of <10 x 109/l) at the time of their intracranial bleed. The presenting features and m...

coincidence of autoimmune diseases such as immune thrombocytopenic purpura (itp) with  immunodeficiencies has  been  reported  previously in  patients  who  suffered  from primary antibody deficiency (pad). but there is no original study on immunological profiles of itp patients to find out their probable immune deficiency. in this case-control study, itp patients’ humoral immunity was investig...

Idiopathic Thrombocytopenic Purpura (ITP) is caused by production of platelet autoantibody. Then ITP can be various viral infections, including Human Immunodeficiency Virus (HIV), Hepatitis C (HCV), cytomegalovirus, herpes simplex virus, Zika virus and others [1].

Prof Şinasi Özsoylu, MD, Department of Pediatrics, Hematology Unit, Faculty of Medicine, Hacettepe University, Ankara 06100 (Turkey) I have read with interest the article by Mazzucconi et al. [1] entitled ‘Danazol Therapy in Refractory Chronic Immune Thrombocytopenic Purpura’ in the recent issue of the journal. I would like to bring to the authors’ attention that marked improvement of platelet ...

Idiopathic thrombocytopenic purpura (ITP) is an immune-mediated thrombocytopenia. ITP is the result of accelerated platelet destruction by the reticuloendothelial system, primarily the spleen. The prevalence of Helicobacter pylori infection and the effect of its eradication were monitored in an ITP patient over a period of 12 months. Eradication of Helicobacter pylori led to the increased plate...

A common misconception is that immune thrombocytopenic purpura (ITP) causes only bleeding diathesis. From this case vignette of a young male with ITP who had cerebral venous thrombosis, we highlight the importance of considering venous thrombosis in such patients when they present with focal cerebral signs.

Severe thrombocytopenia is a cause of morbidity and mortality for patients with COVID-19 infection. The common causes in these are; sepsis, drug-associated, disseminated intravascular coagulation (DIC), heparin-associated (HIT), microangiopathic hemolytic anemia (MAHA). Recently, cases infection-associated Immune thrombocytopenic purpura (ITP) have been reported the literature. In our study, we...