micrornas (mirnas) are small preserved non-coding rna molecules that regulate gene expression post-transcriptionally by targeting the 3' utr of mrnas for translational repression or degradation. the rising evidence has established the significant role of mirnas within the regulation of immune system and the prevention of autoimmunity. mir-146a has obtained an importance as a modulator of d...

the effects of methanolic extract and leaf powder of artemisia annua were studied on performance, cellular and humoral immunity in 240 cobb broiler chicks in a completely randomized design. control group did not receive any treatment. the chicks in the second and third groups were fed with feed which contained 2000 and 4000 ppm plant extract in diet and in the groups 4, 5 and 6 chicks received ...

objectives: the aim of the present study was to investigate immunotoxic effect of safranal (saf), a main component of crocus sativus essential oil, using balb/c mice. materials and methods: saf was administered intraperitoneally at doses of 0.1, 0.5 and 1 ml/kg for 3 weeks. hystopathological examination of spleen and bone marrow, cellularity of spleen, delayed type of hypersensitivity (dth) res...

Sir, Hauton and Smith (BioEssays 29:1138) make the strong assertion that a whole-organism phenomenological approach to investigating invertebrate immunity is flawed and sidesteps scientific rigour. Their major claimappears to be thatweshould not study immunity based on observations at the level of the whole organism, and should instead limit ourselves to measuring the levels, regulation and int...

background: in iran, despite the use of vaccine since 1976, we are still having local epidemics especially in the children aged 15-20 years old. since 1996, the yearly epidemics of measles have been reported in these groups in sistan- baluchestan province, south east of iran. the present study was conducted to determinate the level of immunity in this target population in zahedan. methods: a to...

Summary In order to determine the immunity state against Rubella in 10-19 year old women in urban and rural area of Chahar -Mahal Bakhtiari province of IRAN in act 1992. We have done a cross sectional seroepidemiologic study in 1347 women. This study showed a high rate of immunity against Rubella in this province. About 90.5% of studied population had protective antibody titer against Rubella...

the plant-pathogen interaction is a multifactor process that may lead to resistance or susceptible responses of plant to pathogens. during the arms race between plant and pathogens, various biochemical, molecular and physiological events are triggered in plant cells such as ros signaling, hormone activation and gene expression reprogramming. in plants, micrornas (mirnas) are key post-transcript...

Vaccination of susceptible mice with St. Louis encephalitis virus induced an acquired immunity to intracerebral inoculation which appeared within 1 week. When first demonstrable this immunity was at a very high level and it remained so for about 6 weeks, after which time it declined and disappeared completely between the 12th and 20th week after vaccination. Humoral antibodies of significant ti...