The expression of KiSS-1, MMP-9 and MMP-2 mRNAs and proteins was studied in placentas of women with preeclampsia (PE, n=47) and women of normal pregnancy (NP; n=30). In addition, KiSS-1 mRNA expression as well as cell growth, proliferation and invasion were examined in JAR cells (human trophoblast cell line) transfected with pcDNA3-KiSS-1vector. Expression of KiSS-1 mRNA and protein was higher ...

This paper describes how to resign Jar files. Jar files (Java archives) are used by technologies (like Java Web Start) to deploy applications that are run with increased privileges. The Jar files are signed with certificates that generally expire after a year. The annual resigning of the files is therefore an event that occurs after the signer has forgotten how resigning is done. Manual resigni...

Java Archive (JAR) file is a popular way to aggregate Java class files and resources into one package for distributing applications and/or libraries. JAR file format is developed based on the popular ZIP file format, while providing a convenient way to organize Java byte code for distribution in the open source community, JAR added extra layer of encapsulation and made it more difficult to tell...

At the initial phase of embryo implantation, the trophoblast of the blastocyst has to establish contact to the free surface of the uterine epithelial cells (UECs) and to adhere there. Adhesion to an apical plasma membrane is a very unusual phenomenon, and mechanisms involved are poorty understood. Determination of binding forces using atomic force spectroscopy demonstrated that formation of str...

Notch signaling pathways play important roles in cell fate and many diseases, including preeclampsia, the dysregulation of which may be the main cause of maternal mortality. This study aimed to investigate the roles of Notch2 and Notch3 in proliferation and invasion in trophoblast cell lines (BeWo and JAR). Small hairpin RNAs targeting Notch2/Notch3 and Notch2/Notch3-overexpression vectors were...

Animals using active sensing systems such as echolocation or electrolocation may experience interference from the signals of neighbouring conspecifics, which can be offset by a jamming avoidance response (JAR). Here, we report JAR in one echolocating bat (Tadarida teniotis: Molossidae) but not in another (Taphozous perforatus: Emballonuridae) when both flew and foraged with conspecifics. In T. ...

Choriocarcinoma, a highly malignant tumor arising from the trophoblast, comprises a heterogenous population of cells including cytotrophoblasts, intermediate trophoblasts, and syncytiotrophoblasts. In order to investigate trophoblast differentiation, we used centrifugal elutriation to separate cells from the JAr choriocarcinoma cell line according to their size and to further show that the resu...

Among many disposal options of animal carcasses due to animal diseases including foot-and-mouth disease (FMD) and avian influenza (AI), on-farm burial has been the most frequently used one in Korea. Animal carcasses generate contaminants such as ammonium-N and chloride. This study aimed at testing biochar (BC) as a permeable reactive barrier (PRB) material in combination with fast growing tree ...

Trichosanthin (TCS) is a ribosome-inactivating protein (RIP) which can inhibit the growth of human choriocarcinoma (JAR) cells. There are no clear mechanisms to discover the interaction pathway and cytotoxicity of TCS in JAR cells. In this paper, we showed the distribution and transport of endogenously expressed TCS in JAR cells. Enhanced Green Fluorescence Protein (EGFP), fused with TCS, was a...