background: macrolides, lincosamides and type b streptogramins (mlsb) are commonly used for the treatment of staphylococcal infections. inducible mlsb resistance (imlsb) cannot be identified by standard methods of antibiotic susceptibility testing. d-test appears to be a reliable indicator of imlsb strains. the aim of this study was to determine the prevalence of clindamycin resistance phenotyp...

conclusions in our study, inducible clindamycin resistance rate was 4%; so it is necessary to conduct d-test regularly by disc diffusion for this bacterium. resistance to erythromycin, clindamycin, ciprofloxacin and gentamicin was significantly higher in mrsa isolates than methicillin susceptible staphylococcus aureus (mssa), although the methicillin resistance prevalence was low. background st...

background: streptococcus group b (gbs) or streptococcus agalactiae is typically associated with neonatal disease and infection in pregnant women. mortality of gbs sepsis in neonates is over 50% and is particularly high in preterm infants. gbs also causes invasive infection in pregnant and non-pregnant women including urinary tract infection (uti). penicillin-derived antibiotics remained as cho...

background: clindamycin inducible resistant staphylococcus aureus (s.aureus) isolates can cause failure in treatment with this antibiotic. biofilm production via polysaccharide intercellular adhesion (pia) contributes in the colonization of s. aureus, resulting in the initiation of different diseases. the aim of this study was to detect icaadbc genes among isolates of s.aureus with inducible re...

background and objectives: resistance to macrolide can be mediated by erm and msra genes in staphylococcus aureus . there are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. the aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msr a genes among s. aureus isolates. ...

Background and Objectives: Staphylococcus aureus is an important cause of nosocomial and community-acquired infections in every region of the world. Clindamycin is one of the alternative agents used to treat S. aureus infections and accurate identification of clindamycin resistance is important to prevent therapeutic failure. Unfortunately, inducible clindamycin resistance is ...

Clindamycin resistance in Staphylococcus species can be either constitutive or inducible. Inducible resistance cannot be detected by the conventional antimicrobial susceptibility test. In this study, we determined the prevalence of inducible clindamycin resistance in staphylococcal isolates at a Korean tertiary care hospital. Between February and September 2004, 1,519 isolates of Staphylococcus...

Background: Antibiotics called macrolide, lincosamide and streptogramin B (MLSB) are being used to treat staphylococci infections. Multiple pathways that impart resistance to MLSB antibiotics have been confirmed to cause clinical failure. The present work aimed to determine the frequency of constitutive and inducible clindamycin resistant among coagulase-negative staphylococci (CoNS) isolates o...

BACKGROUND Clindamycin is a frequently used antimicrobial therapeutic medicine used for the treatment of skin and soft tissue infections caused by Staphylococcus aureus strains. Resistance to this antibiotic is either constitutive or inducible. Constitutive resistance to clindamycin could be detected by standard susceptibility testing methods. Inducible clindamycin resistance could not be detec...

Inducible clindamycin resistance in Staphylococcus aureus is of great concern owing to its frequent association with false sensitivity in antibiogram and treatment failure. One hundred and two clinical isolates of Methicillin resistant S. aureus (MRSA) were identified by oxacillin, cefoxitin disc diffusion and oxacillin agar dilution method. Antibiotic susceptibility to erythromycin and clindam...