objective: the study assessed the efficacy of low dose ketoconazole in addition to clomiphene citrate ( cc) and hmg on ovulation induction. materials and methods: a double blind, randomized, clinical trial was performed on fifty infertile patients with pcos who had failed to respond to a daily dose of hmg and 100 mg cc for controlled ovarian hyperstimulation in vali-e-asr reproductive health re...

objective: to compare the effectiveness of letrozole and clomiphene citrate (cc) on uterine blood flow rate in patients with unexplained infertility. materials and methods: in this randomized clinical trial 90 women with unexplained infertility referred to a university clinic from january 2011- december 2013 were enrolled. thirty patients were randomized for letrozole, 30 patients for cc and 3o...

context correct timing of diagnostic laparoscopy for unexplained infertility management remains as a debate for clinicians. a cost-effective strategy of diagnostic laparoscopy utilization for unexplained infertile patients is much needed. evidence acquisition detailed evaluation of the articles extracted from a “pubmed” and “cochrane database” search using “unexplained infertility and diagnosti...

background: the effect of smoking cigarettes is followed by diverse effects on ovaries and developing follicles but the effect of passive smoking on ovarian function is unknown. on the other hand, the ovarian response to induction is a very important step in assisted reproduction. the aim of this study is to compare ovarian response in passive smokers and non-passive smokers in an assisted repr...

combination therapy with clomiphene citrate plus gonadotropin (clomiphene citrate plus hmg) in induction ovulation reduce the gonadotropins dose but antiestrogenic effect of c.c. can decrease pregnancy rate. in a randomized clinical trial we compared 3 treatment protocol for induction ovulation and intra uterine insemination (i/o plus iui) in women with infertility history more than one year, n...

objective: the aim of this study was to evaluate and compare the population of natural killer t lymphocyte (nkt) in the uterus and spleen of the hyperstimulated and control mice at the seventh day of pregnancy. materials and methods: the superovulated and control mice were put individually in a cage with a male mouse. in the next morning they were considered for observing the vaginal plag. the...

background: the retrieval of good quality oocytes that is accomplished with selection of the best induction ovulation protocol on the basis of patients condition, age and cause of infertility, is one of the most important aspects of art cycles. the objective was to evaluate the efficacy of low dose, long acting gnrh-a (decapeptyle) for pituitary desensitization and outcome of art compared to lo...

objective: since there is still controversy regarding the best first-line choice for ovulation induction (oi) other than clomiphene citrate (cc) in infertile women diagnosed with polycystic ovary syndrome (pcos), the aim of the present study was to compare recombinant human fsh with cc as the first course of oi in these women. materials and methods: in this pilot randomized controlled trial, 10...

background: heterotopic abdominal pregnancy is a rare entity which poses unique management challenges. case: a 24-year-old gravida 1 woman with history of two years infertility and treatment with clomiphene citrate presented with acute right lower quadrant abdominal pain. heterotopic abdominal pregnancy was recognized at 16 weeks gestation by transvaginal ultrasound scan. we aimed to remove ect...