Background Immediate hypersensitivity reactions to food are a major health concern for Canadians due to severity of reactions they elicit and their increasing prevalence. Currently 6% of children develop food allergy. Peanut (PN) hypersensitivity is one of the major causes of foodrelated anaphylaxis. We tested the hypothesis that the route of initial exposure to food antigen dictates the nature...

Human exposure to hydrocarbons (HCs) is a common problem. In 2010, U.S. poison centers reported 43,000 exposures to HCs, with the majority of cases managed in an outpatient setting. Exposure to HCs of patients who present to the emergency department (ED) can generally be classified into four types. The first is the accidental ingestion involving children younger than 5 years. This is the most c...

Reactive oxidizing species are implicated in the etiology of a range of inhalational pulmonary injuries. Consequently, various free radical scavengers have been tested as potential prophylactic agents. The sulfydryl compound, N-acetylcysteine (NAC) is the only such compound clinically available for use in realistic dosages, and it is well established as an effective antidote for the hepatic and...

conclusions despite the adverse effects of inhalational halogenated anesthetics (especially halothane) on hepatic patients when necessary. the effects on all systems must be considered and the necessary preparations must be provided. these drugs are still used, if necessary, due to the presence of positive effects and advantages mentioned in other studies as well as the adverse effects of other...

Since October 3, 2001, CDC and state and local public health authorities have been investigating cases of bioterrorism-related anthrax. As of November 28, a total of 23 cases have been identified; 11 were confirmed as inhalational anthrax, and 12 (seven confirmed and five suspected) were cutaneous. Epidemiologic investigations to identify the source of exposure to Bacillus anthracis continue fo...

Anthrax is a highly contagious and potentially fatal human disease caused by Bacillus anthracis, an aerobic, Gram-positive, spore-forming rod-shaped bacterium with worldwide distribution as a zoonotic infection in herbivore animals. Bioterrorist attacks with inhalational anthrax have prompted the development of more effective treatments. Antibodies against anthrax toxin have been shown to decre...

CONTEXT Halogenated inhalational anesthetics are currently the most common drugs used for the induction and maintenance of general anesthesia. Postoperative hepatic injury has been reported after exposure to these agents. Based on much evidence, mechanism of liver toxicity is more likely to be immunoallergic. The objective of this review study was to assess available studies on hepatotoxicity o...

ON OCTOBER 9, 2001, A LETter containing anthrax spores was mailed to a US senator’s office in Washington, DC. That letter was processed at the Brentwood postal facility, one of the largest in the Washington, DC, metropolitan area, and eventually opened by the senator’s staff 6 days later. As of October 30, 2001, 5 postal workers who worked at or handled bulk mail from that facility had been hos...