BACKGROUND Nicotine replacement therapy is an effective treatment for nicotine-dependent smokers. However, cessation rates are modest, and preliminary studies suggest that combination therapy may be superior. We compared the efficacy of the nicotine inhaler plus nicotine patch vs nicotine inhaler plus placebo patch for smoking cessation. METHODS A double-blind, randomized, placebo-controlled ...

The lung dose and deposition patterns of drug delivered by dry powder inhaler are not known. The effects of inhaling 400 micrograms salbutamol delivered by dry powder inhaler (two 200 micrograms salbutamol Rotacaps), by pressurised metered dose inhaler, and by Acorn nebuliser were studied in nine subjects with chronic stable asthma. Technetium-99m labelled Teflon particles were mixed with micro...

OBJECTIVES To explore whether an association exists between health care professionals' (HCPs) asthma knowledge and inhaler technique demonstration skills. METHODS HCPs' asthma knowledge and inhaler technique demonstration skills were assessed at baseline at an inter-professional educational workshop focusing on asthma medication use. Asthma knowledge was assessed via a published questionnaire...

BACKGROUND Good inhaler technique and medication concordance is important for symptom and disease control in chronic airways disease. OBJECTIVES Establish the prevalence of inhaler use; the main inhaler devices used by older people at home; their ability to use the inhalers they have been prescribed; and the relationship between perceived ease of use and actual performance. DESIGN Cross-sec...

OBJECTIVES To assess the proportion of critical errors committed while demonstrating the inhaler technique in hospitalized patients diagnosed with asthma and chronic obstructive pulmonary disease (COPD).  METHODS This cross-sectional observational study was conducted in 47 asthmatic and COPD patients using inhaler devices. The study took place at King Abdulaziz Medical City, Riyadh, Saudi Ara...

Methods We designed a device with a high fidelity microphone and small sized acoustic storage to make time stamped acoustic recordings of an individual’s use of an inhaler. We related the acoustic features to the various steps involved in the correct use of an inhaler. We established a minimum acoustic profile required to use the inhaler correctly, thereby objectively quantifying technique. A c...

BACKGROUND Traditionally inhaled treatment for asthma has been considered as preventer and reliever therapy. The combination of formoterol and budesonide in a single inhaler introduces the possibility of using a single inhaler for both prevention and relief of symptoms (single inhaler therapy). OBJECTIVES The aim of this review is to compare formoterol and corticosteroid in single inhaler for...

background: chronic obstructive pulmonary disease (copd) is a major health dilemma and cause of morbidity and mortality in either industrialized or developing countries and inhaled corticosteroids are widely used worldwide in these patients. in this systematic review, we aimed to analyze the effectiveness of these gents compared to placebo. methods: pubmed and google scholar literature search h...

Asthma and chronic obstructive pulmonary disease (COPD) are two of the most prevalent chronic respiratory disorders. Over 800 million people suffer from these diseases and over four million people die annually. Although both asthma and COPD are incurable, symptoms can be effectively controlled through the delivery of medication to the lungs. Inhaler devices are employed to deliver medication to...

asthma affects an estimated 300 million people worldwide. poor compliance with the prescribed medication leads to increased mortality and morbidity. various determinants of compliance have been described. the purpose of this study was to determine factors that can influence patients' compliance with prescribed metered dose inhaler drugs. 179 patients with diagnosis of asthma were selected from ...