Developments in medical technology, healthcare delivery, and commercial interests in medicine have increased both the potential for conflicts of interest on the part of physicians, and doubts over the sufficiency of patient autonomy as a justification for administering innovative therapy. The legal and regulatory treatment of innovative therapy is therefore an important question, on which there...

Periodontal disease is a multifactorial disease associated with destruction of supporting periodontal tissues of the tooth caused by certain periodontopathogenic species of bacteria or their toxic products by means of a biofilm formation. The conventional methods to treat periodontal diseases are the mechanical removal of the biofilm and adjunctive use of antibacterial disinfectants or various ...

Psoriasis is one of the most common skin diseases. A variety of molecular alterations has been identified in the active, lesional epidermis and dermis of psoriasis, but the pathogenesis still remains unexplained. Therefore, all antipsoriatic therapeutic regimens are symptomatic. Although there is no cure for psoriasis, a variety of therapeutic modalities is available to reduce the severity and ...

© Annals of Joint. All rights reserved. Ann Joint 2017;2:23 aoj.amegroups.com Muscle weakness and decreased functional capacity are common after knee surgery. Recovery duration and success strongly depend on post-surgery rehabilitation. Although neuromuscular electrical stimulation (NMES) therapy has been used for more than 30 years for muscle rehabilitation and strengthening after orthopedic s...

More than 74 0001 patients with acute ischemic stroke have been randomized into clinical trials over the past 35 years to investigate new therapies.1 Only one treatment, thrombolysis with recombinant tissue plasminogen activator, has emerged from these investigations.2 Efforts to establish acute neuroprotectant therapies have yet to succeed.3,4 Have we squandered our resources? Has methodologic...