Introductoin: Increased level of serum IL-6 is related to development of type 2 diabetes and insulin resistance. The American Diabetes Association and the American College of Sports Medicine recommend that combination of resistance and aerobic exercise is favorable for patients with type 2 diabetes. The purpose of this study was to investigate the effect of 8 weeks of aerobic exercise and concu...

Introduction: Vaspin is a new adipokine which is a member of serine protease inhibitor family and might improve insulin sensitivity. The aim of this study was to investigate the effect of concurrent training (aerobic and resistance) on vaspin, and C-reactive protein levels in middle-aged sedentary obese men. Materials and Methods: 20 sedentary obese men (age: 50.7 ± 2.1 years, the percent of bo...

Background: Cardiomyopathy is one of adverse effects of diabetes that associated with cardiac muscle metabolism and function disruption. Exercise training decreases adverse effects of diabetes on heart by changing genes involved in cardiac metabolism and increasing myokines secretion. So, the aim of this study was to investigate of 8 weeks aerobic training on cardiac PGC-1α gene expression and ...

Introduction: Progranulin (PGRN) has been recently introduced as a new indicator of chronic inflammatory response in type 2 diabetes. The present study aimed to investigate the effect of combined training on serum levels of progranulin, glycosylated hemoglobin (HbA1c), and insulin resistance in overweight and obese women with type 2 diabetes. Materials and Methods: A total of 36 women were divi...

Background & Aim: The supplements and exercise training are used to diabetes control. The purpose of this study was to investigate the effect of eight weeks high intensity interval training and caffeine intake on glycemic indices and insulin resistance in diabetic rats. Methods: In a quasi-experimental study, 50 Wistar diabetic male rats were randomly divided into five groups including control...

Background & Objective: Irisin is myokine, that is secreted by acute exercise activity from the muscle and increases energy consumption. The purpose of this study was to determine the response of irisin serum and insulin resistance to acute pilates training sessions pilates training in obese sedentary women. Materials & Methods: This research is a semi experimental study with pre-and post-test ...

Background: kallikrein 7 (KLK7), a serine protease with a chymotrypsin-like specificity, is able to cleave human insulin in the A- and B-chain. The aim of this study was to investigate the effects of aerobic exercise training on plasma KLK7 concentration and insulin resistance index (HOMA-IR) in normal and overweight sedentary women. Methods: Twenty-eight sedentary women, aged 24-60 years, v...

Background: Apelin is a novel adipokine that is closely related with insulin resistance and type 2 diabetes. The purpose of the study was to determine the effects of progressive resistance training on plasma concentrations of plasma apelin and insulin resistance in middle-aged men with type 2 diabetes. Methods: twenty seven types 2 diabetic men selected as subjects and were rand...