background evidence indicates that insulin resistance results in poor sustained viral response (svr) in patients with chronic hepatitis c (chc). metformin is an oral hypoglycemic agent which improves insulin resistance. methods we sought to determine if the addition of metformin to the treatment regimen could improve svr in treatment-naive chc patients in a randomized, double-blind, placebo-con...

introduction: the use of exercise along with herbal supplements is one of the recommended methods for controlling obesity and its complications, but its effects have been controversial due to the diversity of training programs and also herbal supplements. hence, the objective of this study was to investigate the effects of 10 week ginger and progressive resistance training on c-reactive protein...

background: obesity is a very common disorder resulting from an imbalance between food intake and energy expenditure, and it has a substantial impact on the development of chronic diseases.  the aim of this study was to examine the association of insig2 (rs7566605) gene polymorphism with obesity and obesity associated phenotypes in north indian subjects. methods: the variants were investigated ...

background: obesity and overweight are accompanied with insulin resistance markers and diagnosed as a metabolic risk factor in prevalence and develop the asthma severity. regardless of biological role of inflammation markers in asthma, the effective mechanisms in relation to obesity and asthma are not fully understood. methods: this study investigates the relationship between insulin resistance...

objective: psoriasis is a chronic inflammatory disease. it may cause poor quality of life. the purpose of this study was to determine the prevalence of insulin resistance in patients with psoriasis to clarify the relationship between insulin resistance and psoriasis. materials and methods: this case-control study was conducted on 110 patients with psoriasis and 110 healthy people. fasting serum...

the purpose of the present study was to investigate the effect of endurance (et), resistance (rt) and concurrent training (ct) on plasma levels of visfatin, insulin, glucose and insulin resistance of non-athlete men with obesity. it was a semi-experimental study. thirty six men [age: 21.48 (0.25), and bf%: 27.39 (0.52)], voluntarily participated in this study after public announcement in univer...

Diabetes mellitus is a group of metabolic diseases. Insulin resistance is defined as a state that needs more insulin to get the biological effects achieved by a lower amount of insulin in the normal state. Several molecules which are secreted through adipocytes have been involved in insulin resistance and type 2 diabetes mellitus. Adiponectin as a 244 amino acid protein is exclusively expressed...

conclusions because of increasing prevalence of prediabetes at earlier age, it seems necessary to reconsider the screening age in urban areas and perform the screening in all adults at younger ages. results the prevalence of diabetes was 7.04% (4.52% women, 2.52% men) and the prevalence of prediabetes was 8.58% (5.59% women, 2.98% men). thehighest prevalence of diabetes and prediabetes were obs...

rabson-mendenhall syndrome is a rare genetic disorder characterized by growth retardation, dysmorphisms, lack of subcutaneous fat, acanthosis nigricans, enlarged genitalia, hirsutism, dysplastic dentition, coarse facial features, paradoxical fasting hypoglycemia, postprandial hyperglycemia, extreme hyperinsulinemia and pineal hyperplasia. herein, we described a 10- year-old girl with physical f...