ABSTRACTAim: To evaluate the effect of intra-canal cryotherapy on interleukin-1βand interleukin-10 expression in teeth with symptomatic apical periodontitis.Methodology: Forty-eight single rooted patients periodontitiswere randomly divided into 4 groups according to irrigation protocol.Group I (control); 5% sodium hypochlorite at room temperature. Group II; coldsodium (2-5°C). III; final rinse ...
