Background: Various topical (intracameral) analgesics are used to relieve postoperative pain after cataract surgery. Objectives: We decided compare the effects of intracameral Marcaine and lidocaine on intensity operation. Methods: In this double-blind, randomized clinical trial, 64 patients who were candidates for surgery randomly assigned either anesthesia with or bupivacaine (Marcaine) by in...

Elimination of voriconazole after intracameral injection exhibited an exponential decay with a half-life of 22 min. Voriconazole levels in the vitreous humor were below the detectable limit. The aqueous concentrations achieved with a 25-microg dose during the first 2 h were greater than the previously reported MICs of organisms most involved in fungal endophthalmitis. A rapid decline in intraca...

To determine the origin of peripheral blood mononulclear cells (PBMC) that activate regulatory T cells in anterior chamber-associated immune deviation (ACAID), fluorescein-labeled PBMC were intravenously injected into mice before the mice received an intracameral injection of antigen. Six-24 hr after intracameral injection, fluorescein-labeled PBMC increased in the iris. Twenty-four-48 hr label...

well-designed randomised trial, which examined the effectiveness of an injection of cefuroxime 1 mg in the anterior chamber at the conclusion of cataract surgery. The results showed such a great benefit from the use of cefuroxime that the trial was stopped early, because it was considered unethical not to use the treatment. From these figures, out of 10,000 cataract operations without postopera...

Other measures will also help to reduce the risk of postoperative endophthalmitis: proper hand washing (see ‘how to’ article on page 17), the use of sterile instruments, the ‘non-touch’ technique, the subconjunctival injection of antibiotics,4,5 and the intracameral injection of cefuroxime6 at the end of surgery (see article on page 11). The dose of intracameral cefuroxime must be meticulously ...

Objective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation. Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled. To dilate pupil, one eye was randomly selected to receive intracamerally 1 mL epinephrine hydrochloride 0.001% for 1 minute after corneal incision (...

RATIONALE Glaucoma drainage implant surgery is a treatment option for the management of neovascular glaucoma. However, tube obstruction by blood clot after Ahmed glaucoma valve (AGV) implantation is an unpredictable clinically challenging situation. PATIENT CONCERNS-DIAGNOSES-INTERVENTIONS We report 4 cases using intracameral air injection for the prevention of the tube obstruction of AGV by ...

PURPOSE To assess the duration of the effect of intracameral bevacizumab in patients presenting with rubeosis iridis and neovascular glaucoma (NVG). METHODS Retrospective analysis of 24 consecutive eyes of 24 patients with decompensated NVG (> 21 mm Hg) treated with a single intracameral injection of bevacizumab over a minimum follow-up of 6 months. The endpoint of the study was the need for ...

Intracameral injection of bevacizumab (Avastin) helped in the successful regression of an anterior chamber neovascular membrane in a painful blind eye. The effect was persistent even after six months of follow-up. This is the first report on intracameral administration of bevacizumab with six months of follow-up.