PURPOSE Almost 30% of malignancies in women of developing countries are gynecological and brachytherapy is an integral part of management of these patients. Reports of complications (both acute and late) of high-dose-rate (HDR) intracavitary brachytherapy are sparse in world literature due to relatively small number of gynecological malignancies, particularly in advanced stage, in developed cou...

External-beam radiation therapy with intracavitary high-dose-rate brachytherapy is the standard treatment modality for advanced cervical cancer; however, late gastrointestinal complications are a major concern after radiotherapy. While radiation proctitis is a well-known side effect and radiation oncologists make an effort to reduce it, the sigmoid colon is often neglected as an organ at risk. ...

Background: Cervical carcinoma is the fourth most common cancer and leading cause of related deaths in women worldwide. Brachytherapy an important part treatment cervical cancer. Delivering HDR Intracavitary Covid-19 era challenging. Objective: To compare dosimetry outcomes between two fractionation schedules 9Gy 2 fractions v/s 7Gy 3 high dose rate patients with locally advanced cervix. Method...

PURPOSE Intensity modulated radiation therapy (IMRT) compensation based on 3D high-dose-rate (HDR) intracavitary brachytherapy (ICBT) boost technique (ICBT + IMRT) has been used in our hospital for advanced cervix carcinoma patients. The purpose of this study was to compare the dosimetric results of the four different boost techniques (the conventional 2D HDR intracavitary brachytherapy [CICBT]...

Purpose Intra-fractional organs at risk (OARs) deformations can lead to dose variation during image-guided adaptive brachytherapy (IGABT). The aim of this study was to modify the final accepted brachytherapy treatment plan to dosimetrically compensate for these intra-fractional organs-applicators position variations and, at the same time, fulfilling the dosimetric criteria. Material and metho...

Cervical cancer is a highly preventable malignant disease and if detected early has a good prognosis and can be cured by surgery or radiotherapy alone. In western countries about 40,000 women die from advanced cervical cancer per year, in developing countries, however, where early diagnosis is the exception, the death rate from advanced cervical cancer is about six times as much. The treatment ...

PURPOSE In cervical intracavitary brachytherapy, it is mandatory to evaluate if the doses to bladder and rectum are within tolerance limits. In this study, an effort has been made to evaluate the effect of respiration on the doses to bladder and rectum in patients undergoing brachytherapy. MATERIAL AND METHODS Fifteen patients with cervix cancer treated with concurrent chemoradiation followed...

introduction dosimetric accuracy is a major issue in the quality assurance (qa) program for treatment planning systems (tps). an important contribution to this process has been a proper dosimetry method to guarantee the accuracy of delivered dose to the tumor. in brachytherapy (bt) of gynecological (gyn) cancer it is usual to insert a combination of tandem and ovoid applicators with a complicat...

BackgroundBrachytherapy is an important component in management of cervical cancer, enabling dose escalation with reasonable limitation toxicity. However, some patients, there inadvertent increase OAR (Organs at Risk) doses. In our study, we analyse the dosimetric differences between two commonly used ICBT (Intracavitary Brachytherapy) applicators hospital.MethodsWe performed a retrospective an...

Aim: To analyze the inter-fraction, intra-fraction uncertainties and to verify the delivered total dose with planned dose in the combined intracavitary-interstitial brachytherapy of gynaecological cancer patients using microMOSFET in-vivo dosimeter. Materials and Methods: Between May 2014 and March 2016, 22 patients who underwent brachytherapy treatments with an applicator combination of CT/MR ...