Rupture of an intracranial aneurysm is a life-threatening event. Only one third of intracranial aneurysms rupture during a patient's lifetime. Accurate markers that predict which intracranial aneurysms rupture and which do not are currently lacking in routine clinical practice. Therefore, the treatment decision is a careful balance between the natural history of the intracranial aneurysm and th...

Intracranial aneurysm is a balloon or sac-like dilatation of blood vessels inside the brain. Despite their importance, the biological mechanisms of intracranial aneurysms are not totally understood. We used public genome-wide gene expression profile data to identify potential genes that are involved in intracranial aneurysm in order to construct a regulation network. Some of the transcription f...

conclusions bscta is easily accessible, less time consuming, and most importantly, a non-invasive technique for detecting intracranial aneurysms. it is also suitable for patients who have been referred to emergency services. therefore, it can be used in emergency conditions and as a first-line diagnostic method in patients with non-traumatic sah. patients and methods sixty consecutive patients ...

background : ruptured cerebral aneurysms (icas) are the most common non-traumatic cause of subarachnoid hemorrhage (sah) that is associated with life threatening complications such as vasospasm, infarction, and hydrocephalus (hcp). the active participation of macrophage/monocyte-mediated inflammatory response in the pathogenesis of cerebral aneurysm as labeled with monocyte chemoattractantprote...

Mechanisms of formation and growth of intracranial aneurysms are poorly understood. To investigate the pathophysiology of intracranial aneurysms, an animal model of intracranial aneurysm yielding a high incidence of large aneurysm formation within a short incubation period is needed. We combined two well-known clinical factors associated with human intracranial aneurysms, hypertension and the d...

BACKGROUND It is a common belief in medical community that lunar phases have an impact on human health. A growing body of evidence indicates that lunar phases can predict the risk to develop acute neurological and vascular disorders. The goal of present report was to present our institution data and to perform systematic review of studies examining the association of intracranial aneurysm ruptu...

BACKGROUND AND PURPOSE Approximately 6% of human beings harbor an unruptured intracranial aneurysm. Each year in the United States, >30 000 people suffer a ruptured intracranial aneurysm, resulting in subarachnoid hemorrhage. Despite the high incidence and catastrophic consequences of a ruptured intracranial aneurysm and the fact that there is considerable evidence that predisposition to intrac...

Background and Importance: Intracranial pial arteriovenous fistula is a recently described matter as a rare vascular malformation occurring in children. It is usually located in the subpial space in the intracranial cavity with a high-flow shunt. Case Presentation: Authors report on a 2-year-old child with intracranial pial arteriovenous fistula and progressive enlargement of he...

o bjectives: to determine the diagnostic accuracy of magnetic resonance angiography (mra) compared to intra-arterial digital subtraction angiography (dsa) in detection of intracranial aneurysms in those suffering from acute subarachnoid hemorrhage (sah). m e thods: this observational diagnostic study was performed at a tertiary teaching hospital and reference center in shiraz, iran. we included...

SUMMARY Formation of de novo intracranial aneurysms is rare. Their etiology is not known, but they are seen in patients with inherited collagen disorders, polycystic kidney disease, and familial history of aneurysms. Most de novo intracranial aneurysms are found 3-20 years after diagnosis of the initial aneurysm. We report the imaging findings in a 46-year-old man who developed a de novo intrac...