skin cancer is one of the most important type of cancers in the world. in this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. in this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of cdkn2a gene. this case-control study w...

ocular surface may be involved by different neoplastic lesions ranging from benign to highly malignant. recognition of risk factors, clinical presentations, pathology, and different therapeutic modalities is essential for selecting an appropriate approach. this article deals with the proper approach to ocular surface squamous neoplasia (ossn) including conjunctival/corneal intraepithelial neopl...

background & objectives:  cd10 is a cell surface enzyme with metalloendopeptidase activity, also known as common acute lymphoblastic leukaemia antigen, which mainly serves as a marker for acute lymphoblastic leukemia (all). to date and to the best of our knowledge, only few comparative immunohistochemical studies have assessed cd10 expression in cutaneous epithelial neoplasms. our goal was ...

UNLABELLED Dentigerous cysts are one of the most common odontogenic cysts of the oral cavity. Odontogenic cysts can give rise to a variety of neoplasms. Carcinoma arising in a dentigerous cyst is extremely rare, with a review of literature showing near 30 cases. The present report describes 2 cases of primary intraosseous squamous cell carcinoma originated from a dentigerous cyst. The first one...

zinc has an important role in skin health and its deficiency reduces immunity. to evaluate levels of zinc in squamous cell carcinoma (scc) and basal cell carcinoma (bcc) of skin, we studied 44 bcc and 38 scc cases together with 33 controls. blood samples were taken and after separation of serum, levels of zinc, albumin and total protein were measured by atomic absorption, albumin kit and reflec...

BACKGROUND The term "primary intraosseous squamous cell carcinoma" was introduced in 2005 by the World Health Organization with three subcategories. Squamous cell carcinoma arising from the lining of an odontogenic cyst is one important rare subcategory of such lesions with an incidence of 0.01 to 0.02%. Furthermore, the appearance of such malignancy in an odontogenic tumor such as keratocystic...

background and aims. there is no report on the apoptotic impact of allium sativum l. (garlic) on the oral squamous cell carcinoma (kb); hence, this study was designed to survey the apoptotic effects of garlic fresh juice (gfj) on the kb cells. materials and methods. mtt assay (microculture tetrazolium assay) was carried out to evaluate the cytotoxicity of gfj on kb cells. furthermore, tunel (te...

â  â  background esophageal squamous cell carcinoma (escc) is usually detected in advanced stages resulting in a very poor prognosis. early diagnoâ­sis needs identification of clinically relevant precancerous lesions which could become the target of screening and early treatment. our aim was to check whether esophagitis could serve as a relevant histological precursor of escc in northern iran. ...

Medication-related osteonecrosis of the jaw (MRONJ) has been associated with use different drugs administered in treatment malignant neoplasms or metastases and antiresorptive therapies. Since 2010, denosumab, a monoclonal antibody whose mechanism action is to prevent activation RANK receptor on surface osteoclasts, jaw. Primary intraosseous squamous cell carcinoma (PIOSCC) rare neoplasm charac...