Background: Medullary breast carcinoma (MBC) is a unique histological subtype of breast cancer. The present study aimed to evaluate the classic and non-classic characteristics of MBC and its differences with IDC. The present review study incorporates 22 years of practical experience from a breast disease research center-based series of cases.Methods: Retrospectively, the medical records of 3,24...

Background: Breast cancer is the most common malignancy in females worldwide. Several etiological factors including environmental factors have been recognized for breast cancer. Epstein Barr virus as a viral etiological factor has been proposed. So far, several studies have investigated the relationship between development of breast cancer and Epstein Barr virus, but few have been done in Iran....

BACKGROUND Invasive ductal carcinoma is a kind of very typical breast cancer. The goal of our research was to figure out the molecular mechanism of Invasive ductal carcinoma and to find out its potential therapy targets. RESULTS The total amount of 478 differentially expressed genes in Invasive ductal carcinoma which compared with normal breast epithelial cells were recognized. Functional enr...

We investigated the expression of membrane type-1 (MT1)-MMP, MMP2, MMP9 and TIMP2 mRNAs and their roles in ductal carcinoma in situ (DCIS) and T1 and T2 invasive ductal carcinoma of the breast. We further compared these two types of carcinomas for differences in microvessel density, and expression of angiogenic factors and CD44std. MT1-MMP, MMP2, MMP9 and TIMP2 mRNA were expressed in both DCIS ...

The transition from ductal carcinoma in situ to invasive ductal carcinoma is a key event in breast cancer progression that is still not well understood. To discover the microRNAs regulating this critical transition, we used 80 biopsies from invasive ductal carcinoma, 8 from ductal carcinoma in situ, and 6 from normal breast. We selected them from a recently published deep-sequencing dataset [Fa...

background: breast cancer is the most common malignancy in females worldwide. several etiological factors including environmental factors have been recognized for breast cancer. epstein barr virus as a viral etiological factor has been proposed. so far, several studies have investigated the relationship between development of breast cancer and epstein barr virus, but few have been done in iran....

CONTEXT AND OBJECTIVE Breast cancer is thought to derive from progressively aberrant, non-invasive breast lesions, but it is not known exactly how invasive breast cancer develops from these lesions. The aim of this study was to verify the changes in c-erbB-2 and p53 protein expression between non-neoplastic ducts, ductal carcinoma in situ and invasive ductal carcinoma found in the same breast. ...

Synchronous bilateral male breast cancer is a very rare entity and invasive lobular carcinoma is less common in male breast cancer (MBC) than in female breast cancer (FBC). A 51-year-old man presented with a palpable mass in the left breast was finally diagnosed synchronous bilateral MBC, one an invasive lobular carcinoma and the other an invasive ductal carcinoma. It remains a matter of debate...

Benign epithelial lesions with no significant tendency to malignant transformation include: adenoma: -Ductal -lactating -Tubular adenosis: -apocrine -blunt duct -microglandular -sclerosing fibroadenoma radial scar/complex sclerosing lesions Invasive breast carcinomas are divided into two major categories on the basis of their cytoarchitectural features: Invasive ductal carcinoma: -acinic cell c...