Palladium complexes immobilized onto generation 0-3 PAMAM dendrimers supported on silica were used as catalysts for the carbonylation of iodobenzene in methanol to form methyl benzoate. High yields were obtained and the catalyst was recycled 4-5 times without significant loss of activity. The carbonylation reaction was found to be applicable to a variety of iodoarenes regardless of the nature o...

Soluble polymer-supported convergent synthesis has for the first time been successfully exploited for parallel library synthesis; sub-libraries of tripeptide iodoarenes and arylboronic acids reacted smoothly in a multipolymer PdII-catalyzed Suzuki coupling reaction to generate a library of bisaryl-linked hexapeptides.

This paper reports a one-pot synthesis of the title bromides from both activated and deactivated iodoarenes which are first oxidized with anhydrous NaBO3·H2O/Ac2O/conc.H2SO4 liquid mixtures, then coupled in situ with benzene and activated arenes and, finally, precipitated out with a KBr solution; this method is easy, cheap, safe and fairly effective.

One-pot synthesis of symmetric 1,4-disubstituted 1,3-diynes from iodoarenes and propiolic acid via Sonogashira reaction followed by Pd-catalyzed decarboxylative homocoupling is developed in high yields. Also, this system allows the one-pot synthesis of unsymmetric 1,4-disubstituted 1,3-diynes by cross-coupling of two different 3-substituted propiolic acids.

Easy, safe, and effective novel methods for preparing either (diacetoxyiodo)arenes, ArI(OAc)2, or iodylarenes, ArIO2, from the corresponding iodoarenes, ArI, using sodium periodate as the oxidant are presented in this paper. In order to obtain 2and 4iodylbenzoic acids, the respective sodium salts of 2and 4-iodobenzoic acids should be used as the starting substrates, because mixtures containing ...

An easy and safe, though only moderately effective method is presented for preparing (diacetoxyiodo)arenes, ArI(OAc)2, from iodoarenes, ArI, using the commercially available and easily handled urea-hydrogen peroxide adduct (UHP) as the oxidant. The reactions take place in anhydrous AcOH/Ac2O/AcONa (a catalyst)mixtures, at 40 oC for 3.5 h to afford the purified ArI(OAc)2 in 37-78% yields. The fu...

The formation of Pd(0) in the absence of any classical reducing agent in a medium containing Mg(2+)/Al(3+) layered double hydroxide (LDH) and N,N-dimethylformamide was evidenced. XRD analysis showed the presence of crystalline phases of palladium in the Pd/LDH composite. Suzuki-Miyaura reactions in aqueous medium were carried out at room temperature, and good yields were obtained with bromoaren...

The performance of several palladium precatalysts, namely, palladium(II) acetate, palladium(0) nanoparticles encapsulated into poly(amidoamine) (PAMAM) dendrimers (Pd DENs), and palladium(II)-PAMAM complexes, in the Stille reaction between trichloro(phenyl)stannane and iodoarenes in water is compared. The reactivity of Pd DENs is similar or inferior to that of palladium(II) acetate, although th...