During recent decades increasing interest has been shown in the development of biosensors based on ion sensitive field effect transistors (ISFETs). Many ISFET– based pH sensors have been already commercialized and attempts have also been made to commercialize ISFETbased biosensors for applications in the fields of medical, environmental, food safety, military and biotechnology areas. The growin...

A novel single silicon thin film field-effect-transistor (FET) is developed for use as a sensor to monitor transport and chemical properties of liquids in microfluidic systems. The sensor elements which are compatible with existing (bio-)chemical sensor schemes based on ion-sensitive-field-effect-transistors (ISFET) can detect capillary filling speed and level in aqueous solutions. Using a tran...

Over the past decades, considerable development and improvement can be observed in area of ion-sensitive field-effect transistor (ISFET) for biosensing applications. The mature semiconductor industry provides a solid foundation commercialization ISFET-based sensors extensive research has been conducted to improve performance ISFET, with special focus on materials, device structures, readout top...

it has been recently shown that manufacturing p-n-junctions, field-effect and bipolar transistors, thyristors in a multilayer structure by diffusion or ion implantation with the optimization of dopant and/or radiation defects leads to increase the sharpness of p-n-junctions (both single p-n-junctions and p-n-junctions framework their system). due to the optimization, one can also obtain increas...

The detection and quantification of chemical and biological species are the key technology in many areas of healthcare and life sciences. Field-effect transistors (FETs) are sophisticated devices used for the label-free and real-time detection of charged species. Nanowire channels were used for highly sensitive detections of target ion or biomolecule in FET sensors, however, even significantly ...

A novel recognition method for selective determination of the hyoscine N-Butyl bromide (HBB), an antispasmodic agent for smooth muscles, was devised using extended gate field-effect transistor (EG-FET) as transducing unit. For this purpose a PVC membrane, containing hyoscine n-butyl-tetraphenyl borate ion-pair as recognition component, was coated on Ag/AgCl wire, which was connected to the exte...