BACKGROUND In clinical studies, it has been difficult to evaluate the influence of haemodialysis (HD) parameters on HD clearance (CL(HD)) and reduction rate (RR) of non-ionic contrast medium during HD sessions. We therefore predicted clinical values of CL(HD) and RR of iopromide, a non-ionic contrast medium, from findings obtained from in vitro experiments, and confirmed that these predictive v...

background iodinated x-ray contrast media are the most commonly used contrast agents in the world with an annual application of 40-50 million. new non-ionic con- trast agents are subdivided into low osmolar agents such as iopromide and iso-osmolar agents such as iodixanol. regarding different biochemical characteristics, these agents are different in the allergic reactions and contrast enhancem...

BACKGROUND Lipophilic taxanes can be dissolved in contrast media at significantly higher concentration than in saline. As contrast media have occasionally been observed to delineate the contour of coronary arteries for some seconds they may serve as a matrix for an antiproliferative drug aimed at preventing restenosis. The aim of this study was to test a novel taxane-contrast agent formulation ...

Objectives Mechanisms underlying contrast medium (CM)-induced nephropathy remain elusive, but recent attention has been directed to oxygen availability. The purpose of this study was to evaluate the effect of the low-osmolar CM iopromide and the iso-osmolar CM iodixanol on oxygen consumption (QO2) in freshly isolated proximal tubular cells (PTC) from kidneys ablated from elderly humans undergoi...

BACKGROUND Thyroid function disorders have often been observed in preterm infants after intravenous administration of iodinated contrast medium. The effect on thyroid function depends on the dosage, but the choice of the contrast medium may be equally important, as there are appreciable pharmacological differences between them. METHOD Thyroid function was analysed in 20 very low birthweight i...

The degradation of seven compounds which are usually recalcitrant in classical activated sludge treatment (e.g., diclofenac, propranolol, iopromide, iohexol, iomeprol tebuconazole and propiconazole) was studied in a biofilm reactor (slow sand filtration). This reactor was used to treat real effluent-wastewater at different flow rates (hydraulic loadings) under aerobic conditions so removal and ...

The 24th Annual Meeting of the “Deutsche Gesellschaft für Klinische Mikrozirkulation und Hämorheologie” DGKMH E.V. paralleled by the Annual Meeting of the Society for Microcirculation and Vascular Biology GFMVB 17–19 September 2005, Rostock, Germany Local Congress Organisation: Prof. Dr. P. Schuff-Werner and Dr. Birgit Holdt-Lehmann (Rostock) Scientific Committee: Prof. F. Jung (Hoyerswerda), P...

Seizures, alterations in mental and cerebral functions, and ophthalmoplegia are known side effects of contrast agents. Here we report a case of self-limiting monoplegia in a patient after the administration of intracoronary iopromide after coronary angiography which emphasises that, although benign, contrast-induced monoplegia is a neurological disease which requires careful evaluation and a...

BACKGROUND Magnetic resonance arthrography, a procedure through which contrast agents containing gadolinium and/or iopromide are administered intra-articularly, has become a useful tool in musculoskeletal diagnosis. Nevertheless, despite being considered safe for systemic use, certain tissue toxicities have been identified for both drugs. In this study, the effects of short-term exposure of hum...

BACKGROUND Coronary artery disease (CAD) alters the vasomotor response to a variety of pharmacological agents. We tested the hypothesis that CAD also has an impact on the coronary vasomotor response to radiologic contrast media. METHODS AND RESULTS We performed quantitative coronary angiography in 42 patients without angiographic evidence of CAD and 38 patients with CAD in the left coronary a...