introduction: among different kinds of oral cavity cancers, the frequency of tongue cancer occurrence is more significant. brachytherapy is the most common method to cure tongue cancers. long sources are used in different techniques of tongue brachytherapy. the objective of this study is to asses the dose distribution around long sources, comparing different radioisotopes as brachytherapy sourc...

Introduction: Among different kinds of oral cavity cancers, the frequency of tongue cancer occurrence is more significant. Brachytherapy is the most common method to cure tongue cancers. Long sources are used in different techniques of tongue brachytherapy. The objective of this study is to asses the dose distribution around long sources, comparing different radioisotopes as brachytherapy sourc...

Abstract Skin brachytherapy is a successful practice for treating skin cancer patients. Although gamma source like an Iridium-192 (Ir-192) commonly used in the brachytherapy, use of beta Yttrium-90 (Y-90) has also been investigated this purpose. In current study, we simulated dose distribution proposed Y-90 applicator and Ir-192 Leipzig phantom, compared performance each methods three tumors hy...

The aim of this study was to focus on certain characteristic problems associated with Iridium-192 high dose-rate brachytherapy (Ir-192 HDR-BT) in combination with external beam radiation therapy (EBRT) in the treatment of patients with localised prostate cancer. Over a period of 16 years, >2,000 patients with prostate cancer have been treated in Sweden with a combination of two fractions of 10 ...

Currently, translocation of inhaled insoluble nanoparticles (NP) across membranes like the air-blood barrier into secondary target organs (STOs) is debated. Of key interest are the involved biological mechanisms and NP parameters that determine the efficiency of translocation. We performed NP inhalation studies with rats to derive quantitative biodistribution data on the translocation of NP fro...

BACKGROUND Dosimetric characteristics of a high dose rate (HDR) GZP6 Co-60 brachytherapy source have been evaluated following American Association of Physicists in MedicineTask Group 43U1 (AAPM TG-43U1) recommendations for their clinical applications. MATERIALS AND METHODS MCNP-4C and MCNPX Monte Carlo codes were utilized to calculate dose rate constant, two dimensional (2D) dose distribution...

Purpose: A simple method for verifying the dose point kernel of Ir-192 source used in HDR brachytherapy using Kodak EDR2 film in a spiralphantom. Method and Materials: A spiral solid water phantom availablefrom Gammex International for IMRT QA was modified for this study. A CT scan image of the phantom was acquired with a 10 x 12 inch filmloaded in the spiral groove. A 3.5 mm long 8...