iron overload is a clinical problem which can be prevented by using iron chelating agents. an alternative method of relieving iron overload is to reduce iron absorption from the intestine by administering specific iron chelating agents, which can bind iron to form nonabsorbable complexes. based on this strategy, a series of polymeric ligands containing the chelating moiety 3-hydroxypyridin-4-on...

In the title compound, [Fe(C(11)H(13)ClNO)(2)], the Fe(II) atom is four-coordinated in a square-planar geometry by the O and N atoms of two 2-(butyl-imino-meth-yl)-4-chloro-phenolate Schiff base ligands.

transfusion-dependent patients such as those suffering from β-thalassaemia develop a fatal secondary haemosiderosis and consequently a selective iron chelator must be used to relieve such iron overload. 3- hydroxypyridin-4-ones are selective for iron(iii) under most biological conditions, but unlike desferrioxamine, are efficiently absorbed when administered orally. in this study, the synthesis...

The Fe atom of the title compound, [Fe(C(12)H(9)ClNO(2))(2)], lies on a crystallographic twofold rotation axis. The Fe(II) atom is four-coordinated in a tetra-hedral geometry by the O and N atoms of the two Schiff base ligands. The O atom of the furan substituent in the ligand unit is not involved in coordination to the Fe atom.