New drugs are needed for treatment of Toxoplasma gondii infections. We tested derivatives of principles found in Isatis indigotica for in vitro efficacy against T. gondii infection. Indirubin-3'-oxime analogs showed modest micromolar activity, while tryptanthrin derivatives displayed 50% inhibitory doses in the low nanomolar range. Tryptanthrins have potential as anti-Toxoplasma infection thera...

different types of sediment trap have been introduced so far to be used in erosion measuring stations, each with its own advantages and disadvantages in trapping aeolian particles. these traps have different collection and retention efficiency due to aerodynamic conditions. some characteristics such as isokinetic feature of the trap, collection efficiency, time needed to download sediment, capa...

A lignan, lariciresinol, is an important efficacious compound for the antiviral effect of Isatis indigotica, a widely used herb for the treatment of colds, fever, and influenza. Although some rate-limiting steps of the lariciresinol biosynthetic pathway are well known, the specific roles of gene family members in I. indigotica in regulating lariciresinol production are poorly understood. In the...

Three pairs of glycosidic 8,4'-oxyneolignane diastereoisomers, named isatioxyneolignosides A-F (1-6), were isolated from an aqueous extract of Isatis indigotica roots. Their structures and absolute configurations were elucidated by comprehensive spectroscopic data analysis and enzyme hydrolysis. The validity of ΔδC8-C7 values to distinguish threo and erythro aryl glycerol units and Cotton effec...

Different types of sediment trap have been introduced so far to be used in erosion measuring stations, each with its own advantages and disadvantages in trapping aeolian particles. These traps have different collection and retention efficiency due to aerodynamic conditions. Some characteristics such as isokinetic feature of the trap, collection efficiency, time needed to download sediment, capa...