OBJECTIVES Concurrence of coronary atherosclerotic lesions and intracranial aneurysms has been pointed out in several postmortem and clinical studies. However, the relative risk for intracranial aneurysms in patients with ischaemic heart disease remains uncertain. The aim of this study is to elucidate clinically whether ischaemic heart disease is a risk factor for intracranial aneurysms. METH...

Relatives of young patients with ischaemic heart disease have a substantially increased risk of early death from ischaemic heart disease (Slack and Evans, 1966), and family aggregations of death from ischaemic heart disease were noted especially amongst the few patients with essential hyperlipidaemia. Morris, Kagan, Pattison, Gardner, and Raffle (1966) have called attention to the value of rais...

AIMS Coronary risk factors raise the risk of other chronic disorders. We therefore tested the hypothesis that the geographic distribution of ischaemic heart disease mortality is associated with that of other chronic diseases with which it shares risk factors. METHODS AND RESULTS For the 50 provinces of Spain, we collected mortality data for the period 1980-1995 from the national vital statist...