objective: transplantation of mesenchymal stem cells (mscs) can promote functional recovery of the brain after hypoxic-ischemic brain damage (hibd). however, the mechanism regulating msc migration to a hypoxic-ischemic lesion is poorly understood. interaction between stromal cell-derived factor-1α (sdf-1α) and its cognate receptor cxc chemokine receptor 4 (cxcr4) is crucial for homing and migra...

Objective(s): Some histopathological alterations take place in the ischemic regions following brain ischemia. Recent studies have demonstrated some neuroprotective roles of crocin in different models of experimental cerebral ischemia. Here, we investigated the probable neuroprotective effects of crocin on the brain infarction and histopathological changes after transient model of focal cerebral...

objective(s): some histopathological alterations take place in the ischemic regions following brain ischemia. recent studies have demonstrated some neuroprotective roles of crocin in different models of experimental cerebral ischemia. here, we investigated the probable neuroprotective effects of crocin on the brain infarction and histopathological changes after transient model of focal cerebral...

BACKGROUND S100B protein in patients with cardiac arrest, hemorrhagic shock and other causes of global cerebral ischemic injury will be dramatically increased. Ischemic brain injury may elevate the level of serum S100B protein and the severity of brain damage. METHODS This article is a critical and descriptive review on S100B protein in serum after ischemic brain injury. We searched Pubmed da...

Background: Probiotics are microorganisms that may influence brain function via altering brain neurochemistry. New research evidence suggests that probiotic bacteria might protect tissue damage through diminishing the production of free radicals and/or inflammatory cytokines. Therefore, this study was designed to evaluate the effects of probiotic bacteria on the prevention or reduction of brain...

Introduction: There are several different molecular pathways in tissue damage by Ischemic Brain Injury. The use of antioxidants and free radical scavengers are a matter of attention by some researchers. Crocus sativus (saffron) is used previously for protective effects in ischemia state by some researchers. To assess pathologic aspects of neuroprotection of saffron in some susceptible brain are...

introduction: there are several different molecular pathways in tissue damage by ischemic brain injury. the use of antioxidants and free radical scavengers are a matter of attention by some researchers. crocus sativus (saffron) is used previously for protective effects in ischemia state by some researchers. to assess pathologic aspects of neuroprotection of saffron in some susceptible brain are...

Stroke is the world's largest neurological defect caused by the disruption of brain blood circulation. Apart from death, the severest damage caused by stroke, a plethora of other mental and physical disabilities can ensue the incidence of a stroke. As a result of the continued disruption of blood circulation triggered by a stroke, biochemical and physiological mechanisms affect nerve cells and ...