OBJECTIVES We sought to determine the relative impact of diabetes mellitus on prognosis in ischemic compared with nonischemic cardiomyopathy. BACKGROUND Ischemic myocardium is characterized by increased reliance on aerobic and anaerobic glycolysis. Because glucose utilization by cardiomyocytes is an insulin-mediated process, we hypothesized that diabetes would have a more adverse impact on mo...

Cardiac resynchronization therapy (CRT) using a biventricular pacing system has been an effective therapeutic strategy in patients with symptomatic heart failure with a reduced left ventricular ejection fraction (LVEF) of 35% or less and a QRS duration of 130 ms or more. The etiology of heart failure can be classified as either ischemic or non-ischemic cardiomyopathy. Ischemic etiology of patie...

OBJECTIVES The goal of this study was to examine the effect of heart failure etiology on peripheral vascular endothelial function in cardiac transplant recipients. BACKGROUND Peripheral vascular endothelial dysfunction occurs in patients with heart failure of either ischemic or nonischemic etiology. The effect of heart failure etiology on peripheral endothelial function after cardiac transpla...

BACKGROUND Cardiac Resynchronization Therapy (CRT) is indicated for the treatment of advanced heart failure with severe systolic dysfunction and intraventricular conduction delay. Patient selection for this technology is vital, though it remains unclear which patients benefit most from CRT. We tested the hypothesis that patients with non-ischemic cardiomyopathy have a superior mortality benefit...

  Background: Embolus is one of the causes of ischemic stroke that can be due to cardiac sources such as valvular heart diseases and atrial fibrillation and atheroma of the aorta. Transesophageal echocardiography (TEE) is superior in identifying potential cardiac sources of emboli. Due to insufficient data on TEE findings in ischemic stroke in Iran, the present study was done to evaluate TEE in...

In recent decades, cardiac magnetic resonance imaging (CMR) has been established  as a valuable tool in the diagnosis of patients with or at risk heart failure. With its ability to characterize tissue changes myocardium, CMR can provide detailed and clinically useful information about type severity damage. The method is not only important for differentiation ischemic from non-ischemic ...

background: embolus is one of the causes of ischemic stroke that can be due to cardiac sources such as valvular heart diseases and atrial fibrillation and atheroma of the aorta. transesophageal echocardiography (tee) is superior in identifying potential cardiac sources of emboli. due to insufficient data on tee findings in ischemic stroke in iran, the present study was done to evaluate tee in d...

background: several competing geometric and hemodynamic factors are suggested as contributing mechanisms for functional mitral regurgitation (mr) in heart failure patients. we aimed to study the relationships between the severity of mr and the qrs duration and dyssynchrony markers in patients with ischemic or dilated cardiomyopathy. methods: w e prospectively evaluated 251 heart failure patient...

OBJECTIVES We sought to evaluate the association between the extent of coronary artery disease (CAD) and survival in patients with symptomatic heart failure (HF) and to create the most prognostically powerful clinical definition of ischemic cardiomyopathy. BACKGROUND An ischemic etiology of HF is known to be a predictor of adverse outcome; however, there is no uniform definition for ischemic ...

Cardiomyopathies are a group of diseases characterized by the structural and functional abnormalities heart muscles in absence other illnesses that might be responsible for observed myocardial anomaly. Hypertrophic dilated cardiomyopathies most prevalent types. Rare types include restrictive cardiomyopathy with arrhythmia. Dilated has documented prevalence 36 cases per 100,000 population Europe...