A checkerboard microdilution method, performed according to the recommendations of the National Committee for Clinical Laboratory Standards, was used to study the in vitro interaction of terbinafine (TRB) with fluconazole (FLU), itraconazole (ITRA), voriconazole (VRC), and posaconazole (PSZ) in 24 isolates of Candida glabrata with decreased susceptibility to azoles isolated from the oral caviti...

Itraconazole is an orally active triazole antifungal drug which has demonstrated a broad spectrum of activity. It is a potent inhibitor of most human fungal pathogens including Crypro,coccus neoformans (Grant and Clissold, 1989). A recent study by Denning et a1 (1989) revealed the usefulness of itraconazole therapy for cryptococcosis. We also experienced the good result of itra,conazole in the ...

A 12-year-old girl with acute lymphoblastic leukemia was referred to King Faisal Specialist Hospital and Research Center. The diagnosis without central nervous system (CNS) involvement was confirmed on admission, and chemotherapy was initiated according to the Children Cancer Group (CCG) 1882 protocol for high-risk-group leukemia. During neutropenia amphotericin B (AMB) (1 mg/kg of body weight/...

historiography by sunnīs on the subject of the purified imams (a.s.)’s life started along with the shī‘as’ and has continued ever since. the evolutionary development of this trend, which has had its ups and downs proportionate to the cultural vicissitudes of the muslim world, requires undergoing serious studies. despite addressing such issues as the why, the how, and the context of the producti...

Forty non-pregnant Colombian women (ages 18-45) with vulvovaginal candidiasis diagnosis (VVC) were enrolled in a blinded study to compare the efficacy of Itraconazole (ITRA) 400 mg vs. Fluconazole (FLU) 150 mg. Sexual partners received similar therapy. Proteinase detection by the Staib method and minimal inhibitory concentration (MIC) for FLU and ITRA by Etest method were performed in all Candi...

PURPOSE To investigate whether postmenopausal hormone therapy (HT) increases retinal and ONH blood flow (BF) and protects ONH topography and the function of retinal ganglion cells in postmenopausal women (PMW). The effect of estradiol (E(2)) treatment on retinal tissue perfusion was also investigated in ovariectomized rats, an animal model for menopause. METHODS Sixty-four healthy PMW were re...

When a child is adopted from a country abroad, adoptive parents are faced with a myriad of decisions, both before, during and after the adoption process, that have a direct effect on how their child develops. Exploratory research inquired into the motivations behind adopting internationally versus domestically, the adoption process, parent-child relations, the issue of race, and more. The main ...

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N itrate reductase (E C 1.6.6 .2) has been iso lated from 11 Sphagnum (B ryophyta) species and purified up to 500-fold by a procedure involving (N H 4)2S 0 4 p recip ita tion and blue sepharose affinity chrom atography. T he purest fraction show ed a n itra te reductase activity of 7.7 nkat mg p ro te in -1 with N A D P H as the e lectron donor. Beside N A D P H and N A D H , FM N H 2 and — aft...