OBJECTIVE The decision to use in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), or split insemination (IVF-ICSI) in the first cycle is based on the number of motile sperm. Hence, total fertilization failure (TFF) often occurs during IVF cycles, despite normozoospermia. To investigate whether the cumulative motile swim-up spermatozoa percentage at 22 hours post-insemination ...

BACKGROUND Sperm DNA damage is common amongst infertile men and may adversely impact natural reproduction, IUI-assisted reproduction and to a lesser degree IVF pregnancy. The aim of this study was to examine the influence of sperm DNA damage on the risk of spontaneous pregnancy loss after IVF and ICSI. METHODS We conducted a systematic review and meta-analysis of studies on sperm DNA damage a...

OBJECTIVE To validate previously computed correction factors for free β-human chorionic gonadotrophin (fβ-hCG) and pregnancy-associated plasma protein-A (PAPP-A) in in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) pregnancies with hormone treatment and to determine the effect on false-positive rate (FPR). METHODS Retrospective study on 249 IVF and 250 ICSI cases and 20...

During the last decades, many studies have shown the possible influence of sperm DNA fragmentation on assisted reproductive technique outcomes. However, little is known about the impact of sperm DNA fragmentation on the clinical outcome of frozen-thawed embryo transfer (FET) from cycles of conventional in vitro fertilization (IVF) and intra-cytoplasmic sperm injection (ICSI). In the present stu...

Objective: To assess the influence of MII oocyte morphology on the fertilization outcome and embryo development in ART cycles. Since, age may affect the quality of oocyte, the role of women's age was also evaluated following IVF or ICSI cycles. Materials and Methods: 200 MII oocytes from 30 IVF and ICSI cycles were evaluated. The morphology of oocytes that were fertilized in IVF cycles (IVF+) w...

ObjectiveTo identify the risk of stillbirth from in vitro types assisted reproductive technologies compared with spontaneous conception (SC), limited to singleton births.DesignSystematic literature search and chaining on online databases: PubMed, Embase, Scopus.SettingNot applicable.Patient(s)Singleton pregnancies fertilization (IVF) or by IVF intracytoplasmic sperm injection (IVF-ICSI).Interve...

Partial or complete fertilization failure after IVF was reported in 5-10% of cycles. Total fertilization failure in patients with normal sperm parameters is rare but very stressful incident after IVF. To rescue the IVF cycles after total fertilization failure, ICSI of unfertilized oocytes after initial insemination has been reported.We reviewed a 2 years experience of rescue ICSI and analyzed t...

The health economics of IVF and ICSI involve assessments of utilization, cost, cost-effectiveness and ability to pay. In 48 countries, utilization averaged 289 IVF/ICSI cycles per million of population per annum, ranging from two in Kazachstan, to 1657 in Israel. Higher national utilization of IVF/ICSI was associated with higher quality of health services, as indicated by lower infant mortality...

BACKGROUND Generally, intracytoplasmic sperm injection (ICSI) may be the preferable method to treat partial globozoospermia, but whether there exist some correlations between ICSI fertilization rate and the proportion of round-headed sperm or morphologically normal sperm remains open. This study was to explore the correlation between ICSI fertilization rate and the sperm morphology in patients ...

BACKGROUND This study compares the fertilization rate and embryonic development of oocytes randomly inseminated by conventional IVF or ICSI in patients with polycystic ovarian syndrome (PCOS) and normozoospermic semen during IVF cycles. METHODS Sibling oocytes were randomized to be inseminated either by ICSI or IVF. Fertilization rate (two pronuclei/COC), day 2 embryonic morphology and rate o...