background: hyperbilirubinemiais a common problem in newborn infants. it can progress to kernicterus in severe forms, unless an intervention is initiated. the objective of this study was to compare the efficacy of clofibrate with phenobarbital in full-term neonates with nonhemolytic jaundice. methods: this double blind clinical trial study was performed on 60 neonate who were divided randomly i...

glucose 6-phosphate dehydrogenase (g6pd) deficiency is an enzyme deficiency of the red blood cells and the most important disease of hexose monophosphate pathway. the role of hemolysis in the pathophysiology of neonatal jaundice due to g6pd deficiency is in contencious. our aim is to study the role of hemolysis in neonatal jaundice associated with g6pd deficiency. this prospective descriptive s...

BACKGROUND Delay in the presentation of infants with jaundice at the hospital is a reason for the persistence of the severe forms of jaundice. OBJECTIVE The aim was to determine the influence of maternal knowledge on newborn jaundice on their care-seeking practices. METHODS In a cross-sectional survey, mothers whose infants presented with significant hyperbilirubinemia were assessed for kno...

Objective: To investigate the major causes and current management of hyperbilirubinemia in full-term newborns in a general hospital. Methods: The clinical and laboratory data of 1,455 full-term newborns with hyperbilirubinemia in the department of neonatology were collected for retrospective and descriptive analysis. Univariate logistic analysis was used to compare the risk factors for hyperbil...

Detailed clinical observations by Hench (1933, 1934) established that hepatogenous jaundice ameliorated rheumatoid arthritis and fibrositis. Reports followed of remissions attending jaundice induced by the injection of bile salts and bilirubin (Thompson and Wyatt, 1938), by inoculation with infectious jaundice (Gardner, Stewart, and MacCallum, 1945), and by lactophenin (Hanssen, 1942), in addit...

Objective: Kangaroo mother care (KMC) was reported to be correlated with the time of phototherapy for babies with neonatal jaundice in the previous studies. The purpose of this study was to verify the effectiveness of KMC on phototherapy for neonatal jaundice. Methods: 216 newborn babies with neonatal jaundice were collected in this study and randomly divided into KMC group and control group. 1...

OBJECTIVES To study (i) the incidence and course of jaundice, and (ii) the predictors of significant jaundice in late preterm infants. DESIGN Prospective analytical study. SETTING Urban perinatal center. PATIENTS Inborn late preterm infants (post menstrual age of 34 0/7 to 36 6/7 weeks). METHODS Infants were followed till day 14 of life or till onset of significant jaundice. Relevant ma...

BACKGROUND Hyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. It is a multifactorial disorder with many symptoms. Generally, the physiological jaundice is the most prevalent type however in some regions pathological jaundice is also common. This review article focuses on a brief introduction to jaundice, its types and causes, measuring the bilirubin level, clinical app...

liver injury occurs with many drugs; therefore, a thorough work up is important for establishing the diagnosis. we report a case of trifluoperazine-induced cholestatic jaundice. a 44-year old male with schizoaffective disorder developed an increase in liver enzymes and jaundice after starting treatment with trifluoperazine. workup for other potential etiologies was negative.