High mobility group I (HMGI) proteins are overexpressed in several human malignant tumors. We previously demonstrated that inhibition of HMGI synthesis prevents thyroid cell transformation. Here, we report that an adenovirus carrying the HMGI(Y) gene in an antisense orientation (Ad-Yas) induced programmed cell death of two human thyroid anaplastic carcinoma cell lines (ARO and FB-1), but not no...

Although most cases of low grade (G1) endometrial cancer (EC) do not behave aggressively, in rare instances, can progress in a highly aggressive manner. In this study we analyzed formalin-fixed, paraffin-embedded (FFPE) EC tissues to find novel clinical and biological features to help diagnosis and treatment of G1 ECs s in order to better stratify patient risk of recurrence. A retrospective coh...

the iranian journal of radiation research (ijrr) is now in the eighth year of publication. this journal is the mouth piece of shared idea of dr shahram akhlaghpoor and me, which was established way back in 2002. at that time the main emphasis of the founder members was to make the subject of radiation research attractive and interesting especially for combating cancer and risk assessment. the d...

background: there is a paucity of information about the oral pathology related articles published in a pathology journal. this study aimed to audit the oral pathology related articles published in iranian journal of pathology (iran j pathol)from 2006 to 2015. methods: bibliometric analysis of issues of iran j pathol from 2006 to 2015 was performed using web-based search.the articles published w...

The biological activity of rabbit anti-Yoshida ascites sarcoma (YAS) sera was studied. Immune antisera exhibited cytotoxic effects at a 1:100 dilution on YAS cells in vitro, causing vacuolation and disruption of the cytoplasm accompanied by karyolysis. Rabbit antisera, given i.p. in gradually increasing daily doses over a period of 8 days, completely inhibited the growth of YAS in isogenic Wist...

In vivo, in vitro, and animal learning studies have reported neuroactive effects of Rb1 and Rg1 ginsenosides that may be relevant to human learning and memory. The objective of this study was to assess potential learning and memory benefits of HT1001, a standardized proprietary North American ginseng (Panax quinquefolius) extract containing Rb1, Rg1 and other important ginsenosides, in healthy ...

introduction: citation tracking is a bibliometrics method to analyze the scientific impact of journal articles which can be done through scopus (sc), google scholar (gs), or isi web of knowledge (wos). in the current study, we analyzed the citations to 2006-2012 articles of iranian journal of nuclear medicine (ijnm) in the sc and gs. methods: we retrieved the relevant data from sc and gs offici...