OBJECTIVES To determine the presence of immunoglobulin E-rheumatoid factor in patients with juvenile rheumatoid arthritis and to correlate it with clinical and laboratory parameters. METHODS A multicenter prospective study was carried out from January 1993 to January 1999 with the enrollment of 3 centers of pediatric rheumatology. Ninety-one children with juvenile rheumatoid arthritis diagnos...

background:  we aimed to report outcomes of total hip arthroplasty (tha) in very young patients under the year of 30.   methods:  thirty patients (45 hips) with various indications for tha were retrospectively reviewed radiologically and clinically and analyzed regarding survival, reasons of failure, factors associated with outcomes and postoperative complications.   results:  within a mean fol...

Raised serum IgG and IgM antibody levels to native type II collagen were found in patients with rheumatoid arthritis and in patients with juvenile chronic arthritis. There was a good correlation between the serum IgG and the IgM antibody levels in rheumatoid arthritis and a weaker correlation in juvenile chronic arthritis. Raised serum IgM antibody levels to native type II collagen were found i...

Arthritis is a chronic inflammatory disease with an interaction of various genetic and environmental factors. It is a heterogenous group of disorder with different etiological and pathogenetic mechanisms. Lipid peroxidation is the prevailing mechanism in various inflammatory disorders. Hence the present study is aimed at evaluating the status of pro and antioxidants in the etiology of arthritis...

Thirteen children with difficult systemic onset juvenile rheumatoid arthritis were treated with thalidomide. At 6 months, 11 of the 13 were able to reduce their use of prednisone ( P < .002), with a concurrent improvement in erythrocyte sedimentation rate ( P < .0001) and an increase in hemoglobin level ( P < 0.005). Juvenile rheumatoid arthritis improvement scores >/=50% were obtained by 10 of...

IgM rheumatoid factors capable of complement fixation and activation are commonly present in the sera of adults with rheumatoid arthritis. Hidden complement fixing IgM rheumatoid factor has been demonstrated in the majority of patients with juvenile RA and hidden agglutinating IgM rheumatoid factors have been demonstrated in the serum of adults with seronegative rheumatoid arthritis. We studied...

Fifteen patients with juvenile ankylosing spondylitis were reviewed. Eight presented with extraspinal arthritis. Certain clinical features were of value early in the disease in distinguishing these patients from those with juvenile rheumatoid arthritis: male sex, remittent oligoarthritis, late onset in childhood, relative sparing of hands and wrists, infrequent cervical spine involvement, and n...

OBJECTIVES To describe consultation with an arthritis specialist because of suspected new-onset juvenile rheumatoid arthritis (JRA) and to determine factors associated with prompt consultation. DESIGN Retrospective cohort study. SETTING Physician reimbursement administrative data were obtained for all children aged 16 years or younger in the Province of Québec (Canada). PARTICIPANTS Suspe...

An analysis of age of onset in juvenile rheumatoid arthritis was performed in the last 300 children seen in our clinic. There was a peak age of onset in girls at 1 to 3 years. Distribution of age of onset in boys was bimodal with the first peak at 2 years of age and the second at 9 years. There was no accentuation of frequency in either sex in the 10- to 14-year age group. The distribution of a...