BACKGROUND Antioxidant supplementations have the potential to alleviate the atherosclerotic damage caused by excessive production of reactive oxygen species (ROS). The present study evaluated the effects of prolonged antioxidant treatment on arterial elasticity, inflammatory and metabolic measures in patients with multiple cardiovascular risk factors. METHODS Study participants were randomly ...

When Karim met Nelson Mandela for the second time in 2000, he had his camera in tow, ready to capture a photo of him shaking the hand of his hero. Mandela later wrote the foreword to Karim and his wife's book, HIV/AIDS in South Africa. Karim has witnessed the emergence and exponential growth of the AIDS epidemic in his country, along with the concurrent explosion of tuberculosis. To reverse the...

STCP is the main bus operator in Oporto Metropolitan Area. The experimental phase of using fleet tracking and management systems fitted on public transport began in the late eighties, but only in 2002 the current system (SAEI) involved all the buses of the company. Nowadays, these systems are integral company management systems. In this paper, the experience of a bit more than six years is rela...

A response to and comment on Pre-referral rectal artesunate in severe malaria: a flawed trial, by Karim F Hirji and Zulfiqarali G Premji.