نتایج جستجو برای: keratin 10

تعداد نتایج: 1021581  

Journal: :The Journal of Cell Biology 1990
P A Coulombe Y M Chan K Albers E Fuchs

To investigate the sequences important for assembly of keratins into 10-nm filaments, we used a combined approach of (a) transfection of mutant keratin cDNAs into epithelial cells in vivo, and (b) in vitro assembly of mutant and wild-type keratins. Keratin K14 mutants missing the nonhelical carboxy- and amino-terminal domains not only integrated without perturbation into endogenous keratin fila...

Journal: :Oncology reports 2006
Ichiro Kurokawa Yoshiko Urakawa Yuko Senba Eriko Kawabata Keisuke Nishimura Youichi Omoto Kazuya Tokime Hitoshi Mizutani Airo Tsubura

We report two cases of eccrine porocarcinoma (EPC), one of intrepidermal EPC (IEEPC) and one of intradermal invasive EPC (IDEPC) in an immunohistochemical study of cytokeratins (CK) using nine different anti-keratin antibodies against CK1, 7, 8, 10, 14, 16, 17, 18 and 19. IEEPC expressed terminal differentiated CK1 and CK10. In contrast, IDEPC expressed simple-epithelial keratins such as CK7, 8...

2009
Chang-Hun Lee Pierre A. Coulombe

Keratins, the largest subgroup of intermediate filament (IF) proteins, form a network of 10-nm filaments built from type I/II heterodimers in epithelial cells. A major function of keratin IFs is to protect epithelial cells from mechanical stress. Like filamentous actin, keratin IFs must be cross-linked in vitro to achieve the high level of mechanical resilience characteristic of live cells. Ker...

Journal: :Injury 2011
Natalia Adamskaya Peter Dungel Rainer Mittermayr Joachim Hartinger Georg Feichtinger Klemens Wassermann Heinz Redl Martijn van Griensven

BACKGROUND Low level light therapy (LLLT) is an attractive alternative to enhance wound healing. So far most studies are performed with red or infrared irradiation. However, we recently showed that blue light (470 nm) can significantly influence biological systems, improving perfusion by release of nitric oxide from nitrosyl complexes with haemoglobin in a skin flap model in rats. Here, we comp...

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