The common presenting symptoms of pancreatic cancer are abdominal pain, weight loss, and jaundice. Pancreatic adenocarcinoma presenting with diabetic ketoacidosis is a very rare emergent clinical condition. However, pancreatic ductal cystadenocarcinoma presenting with diabetic ketoacidosis was not reported. We describe a 60-year-old man with pancreatic cystadenocarcinoma presenting with diabeti...

Diabetic ketoacidosis is a medical emergency with somatic and psychological implications in patients with type 1 diabetes mellitus (DM1). Menstrual cycle-related glycemic change is rarely described as a precipitant of diabetic ketoacidosis. We present a case of a 23-year-old female with a history of DM1, on her second day of menstruation, who presents with diabetic ketoacidosis. In absence of o...

December 2010, Vol. 100, No. 12 SAMJ Diabetic hyperglycaemic crisis is a major reason for high-care unit admissions,1 with mortality rates of up to 30%.2-9 It is characteristically classified as ketoacidotic or hyperosmolar.10 Presentations with the combination of ketoacidosis and hyperosmolality are recognised,6,7,11-16 and have variably been described as ketoacidosis with hyperosmolality or h...

fanconi- bickel syndrome (fbs) is a rare type of glycogen storage disease (gsd) characterized by hepatomegaly, proximal renal tubular acidosis (rta) and marked growth retardation. we report a case of fbs presenting with diabetic ketoacidosis and transient neonatal diabetes. a female infant, product of consanguineous marriage presented with diabetic ketoacidosis at age 33 days, and was treated a...

Aims To determine the impact of structured education promoting flexible intensive insulin therapy on rates of diabetic ketoacidosis, and the costs associated with emergency treatment for severe hypoglycaemia and ketoacidosis in adults with Type 1 diabetes. Methods Using the Dose Adjustment For Normal Eating research database we compared the rates of ketoacidosis and severe hypoglycaemia during ...

OBJECTIVE To explore whether the carbon dioxide-bicarbonate (P(CO(2))-HCO(3)) buffering system in blood and cerebrospinal fluid (CSF) in diabetic ketoacidosis should influence the approach to ventilation in patients at risk of cerebral edema. DATA SOURCE Medline search, manual search of references in articles found in Medline search, and use of historical literature from 1933 to 1967. DESIG...

Although severe acidosis is a life-threatening condition owing to its cerebral and cardiac effects, correction of the acidosis with alkali remains a controversial issue in diabetic ketoacidosis. A 22-year-old female patient in diabetic ketoacidosis who was successfully resuscitated after cardiac arrest is presented and a strong case is made for the administration of bicarbonate in severe cases ...

From 23,231 total admission to three chil­dren's hospitals in Teheran over 3years and 6 months to 8 years period, 83 patients were found to have diabetes, 23 per thousand. The incidence of diabetes in children in­creases with age and is maximum in adoles­cence.  In 83 diabetic children 59 were male and 24 female (F /M:(0.4.)  From 83 diabetic patients 25 (31.2p.c.) were admitted with ketoacid...

We herein present the case of a 21-year-old diabetic obese woman who developed ketoacidosis following the administration of ipragliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor. At the time of admission, although her serum glucose level was only 175 mg/dL, laboratory tests showed ketoacidosis. Interestingly, hyperglycosuria persisted, even after the discontinuation of ipragliflozin...

the study by Lever and Jaspan8 that was cited by Dr. Rosival is different from his. These authors do not seem to support the idea of giving sodium bicarbonate to patients with diabetic ketoacidosis. In their retrospective analysis of 95 episodes of severe diabetic ketoacidosis, they concluded that sodium bicarbonate might not confer any special benefits in the treatment of diabetic ketoacidosis...