OBJECTIVE To demonstrate that heated humidified high-flow nasal cannula (HHHFNC) is superior to inhaled hypertonic saline solution (HSS) in improving respiratory distress in moderate bronchiolitis. In addition, it could improve comfort and reduce length of hospital stay (LOS) and admission to Paediatric Intensive Care Unit (PICU). DESIGN Randomised Clinical Trial from 1 October 2010 to 31 Dec...

BACKGROUND AND OBJECTIVE: Heated, humidified high-flow nasal cannula (HHHFNC) is commonly used as a noninvasive mode of respiratory support in the NICU. The safety and efficacy of HHHFNC have not been compared with other modes of noninvasive support in large randomized trials. The objective was to assess the efficacy and safety of HHHFNC compared with nasal continuous positive airway pressure (...

The use of heated humidified high-flow nasal cannula (HFNC) as an alternative to CPAP in neonates has increased in recent years and seems to have gone viral.1 HFNC as a method of respiratory support to aid in extubation has increased in popularity following randomized controlled trials showing no difference in extubation failure rates or other outcomes between HFNC and CPAP in neonates at 26 we...

The treatment of choice for patients with respiratory failure of neuromuscular origin, especially in patients with hypercapnic respiratory acidosis, is noninvasive ventilation (NIV). Endotracheal intubation and invasive ventilation are indicated for patients with severe respiratory compromise or failure of NIV. In recent years, high-flow oxygen therapy and active humidification devices have bee...

Introduction Oxygen therapy is generally provided via nasal cannula, non-rebreathing masks and masks with reservoir bags. These devices have various limitations. Despite showing clear benefits in certain conditions, non-invasive positive pressure ventilation (NIPPV) limits mobilization, restricts communication and oral nutrition and is poorly tolerated by some patients due to discomfort. High-f...

To cite: Bueno Campaña M, Olivares Ortiz J, Notario Muñoz C, et al. Arch Dis Child 2014;99:511–515. ABSTRACT Objective To demonstrate that heated humidified high-flow nasal cannula (HHHFNC) is superior to inhaled hypertonic saline solution (HSS) in improving respiratory distress in moderate bronchiolitis. In addition, it could improve comfort and reduce length of hospital stay (LOS) and admissi...

The most conventional forms of oxygen delivery rely on facemasks, a nasal cannula or nasal prongs. However, the use of these methods is limited by certain drawbacks, including the need for a flow of oxygen higher than 15L/min in case of severe hypoxemia or the dilution of administered oxygen by entrained room air in cases of high inspiratory flow. An alternative to conventional oxygen therapy h...