conclusions aki is common in urology patients. the underlying aetiologies of aki in this group may explain a lower overall mortality, although increasing aki severity remains a marker of patients at higher risk of poor outcomes. the low rate of renal recovery suggests that urology patients who sustain aki are exposed to a significant risk of ckd and its attendant consequences for long term heal...

conclusions this study showed that pcs and mcs score were slightly more than overall results while kdcs was slightly less than overall results. in addition, dialysis adequacy with kt/v between 1 and 1.2 is associated with lower rate of hospitalization. patients and methods a total of 6,930 chronic hemodialysis (hd) patients enrolled. kdcs-sf version 1.3 questionnaire was used to assess the heal...

Introduction. Recent studies have suggested theophylline for prevention of kidney dysfunction in asphyxia. This study was designed to determine whether theophylline could prevent or ameliorate kidney dysfunction in term neonates with perinatal asphyxia. Materials and Methods. We assigned 36 severely asphyxiated term infants (Apgar score ≤ 5) into 2 groups to receive intravenously a single dose ...

Introduction. Nephrin and podocin proteins, encoded by NPHS1 and NPHS2 genes, are essential for the integrity of the glomerular filter. The present study was aimed to investigate whether NPHS1 rs437168 and NPHS2 rs61747728 genetic variants are involved in the susceptibility to nephrotic syndrome (NS). Materials and Methods. This case-control study was performed on 108 children with NS and 97 he...

Introduction. Recent studies report reduced vascular compliance and elevated levels of fibroblast growth factor 23 (FGF23) in patients with autosomal dominant polycystic kidney disease (ADPKD) and preserved kidney function. In the present study, we investigated the relationship between vascular compliance and FGF23 in patients in early phases of ADPKD. Materials and Methods. We studied 54 ADPKD...

Introduction. Fetuin-A (A2-HS-glycoprotein) is a protein that plays several functions in human physiology and pathophysiology. The role of fetuin-A in type 1 diabetes mellitus (DM) has been less studied. We investigated the serum levels of fetuin-A in type 1 diabetic patients with microalbuminuria. Furthermore, the blocking effect of renin-angiotensin-aldosteron system on serum levels of fetuin...

Introduction. Idiopathic nephrotic syndrome (INS) is a common chronic i l lness in childhood and is initially treated with corticosteroids. Recent reports indicate that the incidence of steroid resistance and focal segmental glomerulosclerosis is on the rise. However, these reports involved different ethnic populations. The purpose of this study was to compare the characteristics of INS in Iran...

Introduction. Dysregulation of CD4+ T cell subsets participates in the pathogenesis of immunoglobulin A nephropathy (IgAN). Vitamin D has immunomodulatory functions. This study aims to investigate the regulatory effect of vitamin D3 on T helperregulatory T (Th17-Treg) cells balance in rats with IgAN. Materials and Methods. Sprague-Dawley rats were randomly assigned to a normal group (n = 6), an...