Dimethyl sulphoxide (DMSO) is a relatively simple organic compound with a molecular weight of 78. It has been reported to be exceptionally non-toxic and has been used extensively in biological systems as a cell preservative, including freeze storage (Porterfield & Ashwood-Smith, 1962; Dougherty, 1962), and as a radioprotective agent against X-irradiation in mice (Ashwood-Smith, 1961). Recent cl...

In an earlier paper from this laboratory (Gordon, 1958) it was demonstrated that fluorescein-labeled specific antiserum employed as a cellular stain will differentiate Candida albicans and Candida tropicalis from other yeasts and yeastlike organisms, including the remaining members of the genus Candida. The present report describes the preparation and use of a similar reagent for detection and ...

Introduction Reports of Norwegian or crusted scabies occurring in England are rare (Calnan, 1950). In this condition itching is not a constant symptom, burrows may not be present and the acarus may be found on the head and neck. The acarus is seen within scales and the gross hyperkeratosis may give the skin the appearance of the bark of a tree. Norwegian scabies has been reported in mental defe...

Wound healing is a major burden of healthcare systems worldwide and hydrogel dressings offer a moist environment conducive to healing. We describe cysteine-containing ultrashort peptides that self-assemble spontaneously into hydrogels. After disulfide crosslinking, the optically-transparent hydrogels became significantly stiffer and exhibited high shape fidelity. The peptide sequence (LIVAGKC o...

ASMBS, SOARD, outcome reporting standards Standardized outcomes reporting in metabolic and bariatric surgery Stacy A. Brethauer, MD*, Julie Kim, MD, Maher el Chaar, MD, Pavlos Papasavas, MD, Dan Eisenberg, MD, Ann Rogers, MD, Naveen Ballem, MD, Mark Kligman, MD, Shanu Kothari, MD for the ASMBS Clinical Issues Committee Bariatric and Metabolic Center, Digestive Disease Institute, Cleveland Clini...

Cosmeceuticals are the advances made within the world of dermatological products and the new beckon in skincare. Cosmeceuticals are topical cosmetic– pharmaceutical hybrids intended to enhance the health and beauty of skin. The concept propounded by Dr. Albert Kligman states that “The Cosmeceuticals are topical agents that are distributed across a broad spectrum of materials lying somewhere bet...

R ecent data show that melasma lesions have, in addition to increased pigmentation, more elastosis and vascularization than perilesional skin. The stabilized formulation of Kligman preparation has shown significant improvements in the treatment of melasma. However, most of the treatments only target the pigmentation, and none of them has been demonstrated so far to prevent the frequent relapses...