pharmacology, clinical, toxicity, and site of action where known. In some instances, the mode of action of the drug is also given but this is of course a futile section in view of our ignorance on this subject. References are given throughout the discussion of each drug. This handbook is satisfactory for a neophyte in this field; for the physician or for the intensive investigator, the discussi...

abstract background leukemia is the most prevalent childhood cancer and acute lymphoblastic leukemia (all) constitutes 75% of all cases. the most frequent presenting symptoms are fever, weight loss and pallor. early detection of clinical symptoms positively affects timely diagnosis. the objectives of the present study were to assess frequency of presenting symptoms, laboratory data, immune phen...