These two brand names are too similar, while the international non-proprietary names (INNs) are clearly different: lamotrigine (an antiepileptic) and terbinafine (an antifungal drug).

Previously published Photo Quizzes are now featured in a mobile app. Get more information at http:// www.aafp.org/afp/apps. A 57-year-old woman presented with a largely asymptomatic rash on her feet that began six months earlier. She had infrequent mild pruritus but no other symptoms related to the rash. She had no systemic symptoms such as fever, chills, myalgias, or arthralgias. The rash did ...

Terbinafine (TB, lamisil), a promising world widely used oral-anti-fungal agent, has been used in the treatment of superficial mycosis. In this study, we found that apoptosis but not cell growth arrest was induced by TB (1 microM, for 24 h) in human promyelocytic leukemia (HL60) cells. The apoptotic effect induced by TB in the HL60 cell was not through the general differentiation mechanisms evi...

of oral terbinafine (Lamisil; Sandoz) in the treatment of feline ringworm caused by. Fifteen cats infected with M canis were treated orally once daily with 30 mg/ kg of terbinafine over a 2-week period. Jul 16, 2015. Itraconazole is an antifungal drug that inhibits the growth of fungal organisms by. Overview Itraconazole for Dogs and Cats commonly known as "ringworm" and toenail infections. Rin...

OBJECTIVES Terbinafine (Lamisil), a widely prescribed oral antifungal agent, reportedly induces taste loss in 0.6% to 2.8% of those taking the drug. However, many so-called taste problems reflect olfactory problems, and the sole empirical study published on this topic, based on whole-mouth testing of a single subject, found no terbinafine-related deficit. In this study, we quantitatively assess...

BACKGROUND Several studies have shown that there are an increasing in invasive candidiasis during 2-3 last decades. Although, Candida albicans is considered as the most common candidiasis agents, other non-albicans such as C. glabrata, C. krusei, C. parapsilosis, and C. tropicalis were raised as infectious agents. Resistance to fluconazole among non-albicans species is an important problem for ...

OBJECTIVE Several antifungal agents are indicated for onychomycosis, a fungal infection of the toenails and fingernails. These agents differ in their dosing regimen, efficacy, adverse events profile, potential for drug interaction, and cost. We conducted a pharmacoeconomic analysis of oral and topical therapies for onychomycosis from the perspective of a hypothetical managed care payer to deter...

The following case contains my comments and not those of Sandoz. My team submitted the New Drug Application (NDA) for LAMIISIL®, terbinafine Oral for onychomycosis, fungal infection of toenails and fingernails. We showed efficacy and safety in all six pivotal studies. The FDA granted approval for this indication in adults. While working on new indications for LAMISIL®, I received a call from Dr...