a 45-year-old female patient with a diagnosis of ulcerative colitis complicated with composite lymphoma in the spleen and para-aortic lymph node presented with a one-month history of malaise, weakness and fatigue. only mesalamine kept ulcerative colitis under control. in physical examination, splenomegaly was revealed and pancytopenia was obtained from laboratory data. computed tomography scan ...

primary hepatic lymphoma is a rare malignancy usually presenting with symptoms of fever, hepatomegaly, jaundice and weight loss. this picture mimics infectious and inflammatory disorders and thus delays the diagnosis. here, we present a 47-year old man with prolonged fever who underwent several investigations and, in the meantime, developed fulminant hepatic failure before the diagnosis could b...

Background: Immunophenotyping in the rare group of nodal Peripheral T-cell Lymphomas (PTCL) exposes interesting features such as T-cell marker downregulation and paradoxically, the presence of reactive, clustered large-sized CD20 positive B-cells (B-cell proliferation). Epstein-Barr virus (EBV) has been suggested as a putative etiology in pathogenesis of B-cell lymphoma. We aimed to review the ...

introduction: primary gastric lymphoma (pgl) is a rare tumor, whose differential diagnosis may become complicated without precise immunohistochemistry (ihc) and genetic analysis. case presentation: a 33-year-old woman presented with gastric cancer and had undergone gastrectomy without precise ihc and staging in another center. inappropriate ihc after surgery showed diffuse large b-cell lymphoma...

Primary cutaneous large B-cell lymphoma leg type is a rare andaggressive neoplasm as defined by the recently updated WorldHealth Organization - European Organization for Research andTreatment of Cancer. We report a case of an 80-year-old manwith multiple cutaneous lesions. Here, we review the availableliterature and summarize clinical features and management ofthis type of cutaneous B-cell lymp...