IMPORTANCE Laryngotracheal stenosis (LTS) lacks an ideal animal model to study its unique wound-healing pathophysiology and the effect of interventions. OBJECTIVE To present an in vivo, in situ mouse model of LTS that can be used to investigate its pathophysiology, mechanisms, and interventions for treatment. DESIGN, SETTING, AND SUBJECTS Prospective controlled animal study performed at an ...

OBJECTIVE To assess whether dynamically modulating endotracheal tube (ETT) cuff pressure, by decreasing it during each ventilatory cycle instead of maintaining a constant level, would reduce the extent of intubation-related laryngotracheal injury. DESIGN Single-blind, randomized controlled animal study using a previously validated live porcine model of accelerated intubation-related tracheal ...

OBJECTIVE Laryngotracheal trauma is a rare but clinically important injury. Complications are frequent. Early recognition, accurate evaluation and proper treatment is vital. In order to learn from our past experience and refine our management, we reviewed our cases METHODS Fifteen patients with external laryngotracheal injuries were analyzed retrospectively. The outcome was assessed both in t...

Abstract Background The larynx has multiple composite functions which include phonation, airway protection, and sensory control of respiration. Stenosis the trachea were first recorded by O’Dwyer in 1885 Colles 1886, respectively. Initially, aetiology laryngotracheal stenosis was predominantly infective. Currently, leading cause is iatrogenic injury to complex secondary prolonged ventilation an...

Intubation of the airway can lead to laryngotracheal injury, resulting in extubation failure from upper airway obstruction (UAO). A number of factors can help to identify patients who are at greatest risk for postextubation UAO. Three randomized controlled trials demonstrate that prophylactic corticosteroids decrease the risk for postextubation UAO and probably the need for re-intubation.

Objective: The use of a T-tube to manage complex laryngotracheal lesions, such as tracheal stenosis, tracheomalacia and tracheal injury, has previously been reported by other surgeons in the past. However, further validation of clinical details, including operative management and postoperative care, is needed. Methods: From January 1991 to May 2000, 53 patients, including 24 with post-tracheost...

Methods Thirteen patients with laryngotracheal stenosis were treated. Ten were males and 3 females with an age range of 4–60 years .The cause of airway stenosis was prolong intubation in 10, blunt trauma injury and idiopathic subglottic stenosis in 2 and 1consequence. Preoperative assessment included bronchoscopy, neck and chest CT scan to determine the extension of stenosis. The upper margin o...